LINF_360048000

S-adenosylhomocysteine hydrolase
Leishmania infantum JPCM5 OG6: OG6_100715 OG7: OG7_0003269 48 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 48 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_360030700
tyrosine aminotransferase
— Both
LINF_150018800 ⚠
tryparedoxin peroxidase
— Both
LINF_150018300
glutamate dehydrogenase
— Both
LINF_340044200
vacuolar ATP synthase catalytic subunit A - p
— Both
LINF_260005300
pyridoxal phosphate containing glycine decarb
— Both
LINF_140020000
inositol-3-phosphate synthase
— Both
LINF_340005700
glucose-6-phosphate 1-dehydrogenase - putativ
— Both
LINF_330032000
udp-glc 4'-epimerase - putative
— Both
LINF_030006800
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
LINF_050015100
3-mercaptopyruvate sulfurtransferase
— Both
LINF_330035400 ⚠
metallo-peptidase - Clan ME - Family M16
— Both
LINF_250013300
protein phosphatase - putative
— OG6
LINF_150019000 ⚠
tryparedoxin peroxidase
— Both
LINF_210008800 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LINF_130013600 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LINF_340035100 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LINF_320046900 ⚠
cAMP response protein 1 - putative
— OG7
LINF_150019400 ⚠
protein kinase - putative
— OG7
LINF_330028000 ⚠
phosphoribosylpyrophosphate synthetase - puta
— OG7
LINF_300038100 ⚠
glutamyl-tRNA synthetase - putative
— OG7
LINF_360063600 ⚠
phosphoribosylpyrophosphate synthetase - puta
— OG7
LINF_080010200 ⚠
ribose-phosphate pyrophosphokinase - putative
— OG7
LINF_360053800 ⚠
mitochondrial intermediate peptidase - putati
— OG7
LINF_270014800
WD domain - G-beta repeat - putative
— OG7
LINF_110016000
pyruvate phosphate dikinase - putative
— Both
LINF_360044500 ⚠
cysteine synthase
— OG6
LINF_300011200
nitrate reductase - putative
— OG6
LINF_070014200
N-acetylglucosamine-phosphate mutase - putati
— Both
LINF_190020900 ⚠
mitogen activated protein kinase 4 - putative
— OG6
LINF_330022100 ⚠
mitogen activated protein kinase - putative
— OG6
LINF_360039100
ATP synthase - putative
— Both
LINF_360024000
aldehyde dehydrogenase - putative
— Both
LINF_020005300 ⚠
aminopeptidase P1 - putative
— Both
LINF_250031600 ⚠
aminopeptidase P1 - putative
— Both
LINF_260020700 ⚠
thimet oligopeptidase - putative
— Both
LINF_270033860 ⚠
hypothetical protein (non-ATG)
— Both
LINF_170008800 ⚠
cystathionine beta-synthase
— Both
LINF_130006500 ⚠
protein kinase A regulatory subunit
— Both
LINF_280031400
Vacuolar proton pump subunit B - putative
— Both
LINF_080016200 ⚠
phosphoribosylpyrophosphate synthetase
— Both
LINF_060009000
glutamine synthetase - putative
— Both
LINF_150018600 ⚠
tryparedoxin peroxidase
— Both
LINF_350037700 ⚠
cystathione gamma lyase - putative
— Both
LINF_150022500 ⚠
glutaminyl-tRNA synthetase - putative
— Both
LINF_230005400 ⚠
peroxidoxin
— Both
LINF_230008700
(H+)-ATPase G subunit - putative
— Both
LINF_140010000 ⚠
cystathionine beta-lyase-like protein
— Both
LINF_230006100
GDP-mannose pyrophosphorylase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.