LPAL13_000025700

SLA/LP autoantigen-like protein
Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_104780 OG7: OG7_0009893 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LPAL13_040007100
exosome complex exonuclease RRP40, putative
— Both
LPAL13_350062600 ⚠
adaptin, putative
— Both
LPAL13_300007900
ubiquitin hydrolase, putative
— Both
LPAL13_200023400 ⚠
ubiquitin-like protein
— Both
LPAL13_280014600 ⚠
DNA replication licensing factor MCM2, putati
— Both
LPAL13_180009600
Flagellar-associated PapD-like, putative
— Both
LPAL13_350059200
2OG-Fe(II) oxygenase superfamily, putative
— Both
LPAL13_260010600
hypothetical protein, conserved
— Both
LPAL13_310018100
Protein of unknown function (DUF3638)/Protein
— Both
LPAL13_350051400
WD domain, G-beta repeat/Utp21 specific WD40
— Both
LPAL13_250018600 ⚠
Cullin family/Cullin protein neddylation doma
— Both
LPAL13_230006100 ⚠
Beige/BEACH domain containing protein, putati
— Both
LPAL13_240028000
hypothetical protein, conserved
— Both
LPAL13_320040000
NADH dehydrogenase subunit NI8M, putative
— Both
LPAL13_250015600
hypothetical protein, conserved
— Both
LPAL13_110006100
hypothetical protein, conserved
— Both
LPAL13_110007100
pumillio protein 10, putative
— Both
LPAL13_160010300
hypothetical protein, conserved
— Both
LPAL13_350027000
hypothetical protein, conserved
— Both
LPAL13_310032200 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— Both
LPAL13_250011900
Rab3 GTPase-activating protein catalytic subu
— Both
LPAL13_230025100
Csl4p homologue, putative
— Both
LPAL13_320006400
Armadillo/beta-catenin-like repeat, putative
— Both
LPAL13_220018900
CCR4 associated factor, putative
— Both
LPAL13_180011200
Periodic tryptophan protein 2 homolog, putati
— Both
LPAL13_000008900
hypothetical protein, conserved
— Both
LPAL13_160008100 ⚠
tubulin tyrosine ligase, putative
— Both
LPAL13_200022600
hypothetical protein, conserved
— Both
LPAL13_160018400 ⚠
DNA-directed rna polymerase I largest subunit
— Both
LPAL13_220018500
hypothetical protein, conserved
— Both
LPAL13_000037100
hypothetical protein, conserved
— Both
LPAL13_200044700
GRIP domain containing protein, putative
— Both
LPAL13_200043100 ⚠
target of rapamycin kinase (TOR) kinase 3
— Both
LPAL13_350036000
hypothetical protein, conserved
— Both
LPAL13_140012600
hypothetical protein, conserved
— Both
LPAL13_270015100
parallel beta-helix repeat, putative
— Both
LPAL13_240016900 ⚠
formin, putative
— Both
LPAL13_250018800
hypothetical protein, conserved
— Both
LPAL13_320034100 ⚠
SpoU rRNA Methylase family, putative
— Both
LPAL13_250011200 ⚠
RNA polymerase I second largest subunit, puta
— Both
LPAL13_330035000
hypothetical protein, conserved
— Both
LPAL13_190005300
hypothetical protein, conserved
— Both
LPAL13_190016100
hypothetical protein, conserved
— Both
LPAL13_140010800
WD domain, G-beta repeat, putative
— Both
LPAL13_070009300
RAVE protein 1 C terminal, putative
— Both
LPAL13_070011100
hypothetical protein, conserved
— Both
LPAL13_210024700
ATP synthase F1 subunit gamma protein, putati
— Both
LPAL13_300040500
ATP synthase, epsilon chain, putative
— Both
LPAL13_050009600 ⚠
ATPase alpha subunit
— Both
LPAL13_290026000
aspartyl aminopeptidase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.