LbrM.10.0620

map kinase 3, putative, mitogen-activated protein kinase 3, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102675 OG7: OG7_0000396 34 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 34 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.16.0050
2OG-Fe(II) oxygenase superfamily, putative
— OG6
LbrM.32.2000 ⚠
iron superoxide dismutase, putative
— OG6
LbrM.08.0330 ⚠
iron superoxide dismutase A, mitochondrial
— OG6
LbrM.10.0200
Mitogen-activated protein kinase 10, putative
— OG6
LbrM.05.0310 ⚠
monothiol glutaredoxin, putative
— OG6
LbrM.34.1170 ⚠
thioredoxin-like protein
— OG6
LbrM.18.0230
Activator of Hsp90 ATPase, N-terminal/Activat
— OG6
LbrM.32.1200
exportin 1, putative
— OG6
LbrM.27.2520
GTP binding protein, putative
— OG6
LbrM.32.2010 ⚠
iron superoxide dismutase, putative
— OG6
LbrM.20.3380
phosphomannomutase-like protein
— OG6
LbrM.35.6500
Sucrase/ferredoxin-like, putative
— OG6
LbrM.30.2040
alcohol dehydrogenase, putative
— OG6
LbrM.33.1160
nicotinate phosphoribosyltransferase, putativ
— OG6
LbrM.28.0070
hypothetical protein, conserved
— OG6
LbrM.13.1300
Gamma-soluble NSF attachment protein (SNAP-ga
— OG6
LbrM.12.0030
PITH domain-containing protein
— OG6
LbrM.22.1430
dephospho-CoA kinase, putative
— OG6
LbrM.35.4740
Protein of unknown function (DUF2870), putati
— OG6
LbrM.16.1550
hypothetical protein, conserved
— OG6
LbrM.27.1360
Serine-threonine kinase receptor-associated p
— OG6
LbrM.30.2550 ⚠
formate--tetrahydrofolate ligase
— OG6
LbrM.26.0350 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG6
LbrM.27.1080
TatD related DNase, putative
— OG6
LbrM.30.3450
hypothetical protein, conserved
— OG6
LbrM.21.0560
hypothetical protein, conserved
— OG6
LbrM.33.0490
hypothetical protein, conserved
— OG6
LbrM.20.1910
Aminotransferase class IV, putative
— OG6
LbrM.22.0110
GMP synthase [glutamine-hydrolysing]
— OG6
LbrM.35.7000
hypothetical protein, conserved
— OG6
LbrM.32.2630
hypothetical protein, conserved
— OG6
LbrM.32.2870 ⚠
superoxide dismutase, putative
— OG6
LbrM.23.0170
hypothetical protein, conserved
— OG6
LbrM.32.2860 ⚠
superoxide dismutase, putative
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.