LbrM.29.1350

ATP-dependent Clp protease subunit, heat shock protein 104 (HSP104), putative, atp-dependent chaperone
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_100223 OG7: OG7_0002479 186 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 186 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.25.1640 ⚠
elongation factor 2-like protein
— Both
LbrM.30.2500 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LbrM.30.2450 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LbrM.30.2440 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LbrM.32.2420 ⚠
U5 small nuclear ribonucleoprotein component,
— Both
LbrM.30.2410 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LbrM.22.0930 ⚠
hypothetical protein, conserved
— Both
LbrM.30.2430 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LbrM.35.0260 ⚠
elongation factor 2
— OG7
LbrM.35.0250 ⚠
elongation factor 2
— OG7
LbrM.35.0270 ⚠
elongation factor 2
— OG7
LbrM.28.1760 ⚠
Galactose oxidase, central domain containing
— OG7
LbrM.30.2420 ⚠
heat shock 70-related protein 1, mitochondria
— Both
LbrM.24.2170 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LbrM.28.2350 ⚠
hypothetical protein, conserved
— OG7
LbrM.16.0090 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
LbrM.20.4400 ⚠
kelch domain-containing protein
— OG7
LbrM.35.1610 ⚠
kelch motif containing protein, putative
— OG7
LbrM.24.0490 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LbrM.35.6491 ⚠
hypothetical protein, conserved
— OG7
LbrM.05.0770 ⚠
Mitochondrial glycoprotein, putative
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.31.3070 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.03.0170 ⚠
ABC transporter protein, putative
— OG7
LbrM.17.0220 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.32.1170 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LbrM.19.1110 ⚠
ABC transport system ATP-binding protein, put
— OG7
LbrM.11.0400 ⚠
aminopeptidase, putative, metallo-peptidase,
— OG7
LbrM.20.1170 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LbrM.35.2810 ⚠
cyclin-e binding protein 1-like protein
— OG7
LbrM.22.1030 ⚠
Beta-lactamase superfamily domain containing
— Both
LbrM.14.0880 ⚠
glutathione synthetase, putative
— Both
LbrM.24.0130 ⚠
ankyrin/TPR repeat protein
— OG6
LbrM.14.1540 ⚠
myo-inositol-1-phosphate synthase, inositol-3
— Both
LbrM.23.1090 ⚠
hypothetical protein, conserved
— Both
LbrM.27.1020 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— Both
LbrM.21.0720 ⚠
nucleotide-binding protein, putative
— Both
LbrM.28.2670 ⚠
MRP protein-like protein
— OG6
LbrM.26.0450 ⚠
nucleotide binding protein-like protein
— Both
LbrM.05.0250 ⚠
hypothetical protein, conserved
— Both
LbrM.02.0390 ⚠
casein kinase II, alpha chain, putative
— OG6
LbrM.07.0520 ⚠
hypothetical protein, conserved (fragment)
— Both
LbrM.28.1990 ⚠
Replication factor A protein 1
— Both
LbrM.22.1020 ⚠
Beta-lactamase superfamily domain containing
— Both
LbrM.22.1360 ⚠
Mitochondrial glycoprotein, putative
— OG7
LbrM.01.0190 ⚠
LSM domain containing protein, putative
— OG7
LbrM.32.1190 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.23.0340 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.2220 ⚠
hypothetical protein, conserved
— OG7
LbrM.15.1240 ⚠
cysteine peptidase, Clan CA, family C19, puta
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.