LmjF.10.0690

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_157992 OG7: OG7_0037640 53 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 53 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.20.0280 ⚠
developmentally regulated phosphoprotein-like
— OG7
LmjF.29.2360
aspartyl aminopeptidase, putative
— Both
LmjF.27.1350
hypothetical protein, unknown function
— Both
LmjF.12.0250
cysteinyl-tRNA synthetase, putative
— Both
LmjF.33.1880
hypothetical protein, conserved
— Both
LmjF.24.2020
tubulin folding cofactor D, putative
— Both
LmjF.09.1300 ⚠
PPPDE putative peptidase domain containing pr
— Both
LmjF.24.0490
Leucine Rich repeats (2 copies)/Leucine rich
— Both
LmjF.07.0940
Domain of unknown function (DUF3437), putativ
— Both
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.34.3900 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmjF.35.2340 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.29.1700 ⚠
MORN repeat, putative
— Both
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmjF.09.1310 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmjF.32.1330 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmjF.35.4260 ⚠
predicted zinc finger protein
— OG7
LmjF.14.1170 ⚠
ras-like small GTPases, putative
— OG7
LmjF.10.0195 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmjF.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmjF.31.1480
hypothetical protein, unknown function
— Both
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LmjF.35.1060
hypothetical protein, conserved
— Both
LmjF.21.0180
CHAT domain containing protein, putative
— Both
LmjF.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.35.3500 ⚠
zinc finger protein, putative
— Both
LmjF.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— Both
LmjF.18.1040
5-oxoprolinase, putative
— Both
LmjF.14.0460 ⚠
cystathionine beta-lyase-like protein
— Both
LmjF.15.0430
hypothetical protein, conserved
— Both
LmjF.16.1150
hypothetical protein, conserved
— Both
LmjF.23.1630 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.28.1910
p21-C-terminal region-binding protein, putati
— Both
LmjF.04.0570
DENN (AEX-3) domain containing protein, putat
— Both
LmjF.21.1670
hypothetical protein, conserved
— Both
LmjF.24.0650 ⚠
PPPDE putative peptidase domain containing pr
— Both
LmjF.31.2170
ARM-like helical domain-containing protein
— Both
LmjF.26.1960
nucleolar protein , putative
— Both
LmjF.21.0470
vacuolar sorting-associated-like protein
— Both
LmjF.17.0400
Ring finger domain containing protein, putati
— Both
LmjF.36.2850
hypothetical protein, conserved
— Both
LmjF.35.3230 ⚠
cystathione gamma lyase, putative
— Both
LmjF.13.0200
Lipase (class 3), putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.