LmxM.33.0350

eukaryotic translation initiation factor 5, putative

Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_101859 OG7: OG7_0007078 56 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 56 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LmxM.13.1660 ⚠ chaperonin TCP20, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LmxM.34.3840 ⚠ proteasome beta 2 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	Both
LmxM.32.1930 ⚠ phosphoribosyl transferase, putative, phospho	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	Both
LmxM.36.3760 ⚠ 60S ribosomal protein L10a, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006190 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006190	Both
LmxM.19.0295 ⚠ RNA binding protein	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_006059 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006059	Both
LmxM.34.2270 ATP-dependent RNA helicase-like protein	—	OG6 TCSYLVIO_001373 ↔ TCSYLVIO_004556	OG6
LmxM.29.3040 eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_003333 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003333 ↔ TCSYLVIO_004556	Both
LmxM.30.2970 acetyl-CoA carboxylase	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_004556	Both
LmxM.11.0240 ⚠ proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	Both
LmxM.28.0110 proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004556	Both
LmxM.36.3000 ⚠ ATP-dependent RNA helicase, putative	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	OG7
LmxM.36.6910 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LmxM.27.1260 ⚠ T-complex protein 1, beta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LmxM.34.3860 ⚠ T-complex protein 1, eta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
LmxM.36.3470 ⚠ 2-oxoglutarate dehydrogenase E1 component, pu	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005469 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005469	Both
LmxM.14.0310 ⚠ proteasome alpha 3 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
LmxM.10.0140 ⚠ DEAD/DEAH box helicase, putative, mitochondri	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LmxM.36.1600 ⚠ proteasome subunit alpha type-1, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
LmxM.08.0510 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	OG7
LmxM.31.0400 ⚠ ATP-dependent RNA helicase HEL67	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LmxM.36.2130 ⚠ ATP-dependent RNA helicase DBP2A, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LmxM.08.0080 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LmxM.27.0190 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
LmxM.21.1830 ⚠ proteasome subunit alpha type-5, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
LmxM.28.2080 ⚠ DEAD-box ATP-dependent RNA helicase, mitochon	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LmxM.19.0300 ⚠ RNA binding protein, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006059	OG7
LmxM.36.1650 ⚠ proteasome subunit beta type-5, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	OG7
LmxM.07.0340 ⚠ ATP-dependent RNA helicase DBP2B, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
LmxM.08.1130 ⚠ phosphoribosylpyrophosphate synthetase	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	Both
LmxM.33.2700 eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_003837 ↔ TCSYLVIO_004556	OG6
LmxM.29.0570 spliceosome-associated protein, putative	—	OG6 TCSYLVIO_003119 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003119 ↔ TCSYLVIO_004556	Both
LmxM.36.4910 hypothetical protein, conserved	—	OG6 Tb927.10.2770 ↔ Tb927.11.11010 OG7 Tb927.10.2770 ↔ Tb927.11.11010	Both
LmxM.03.0690 ⚠ DEAD/DEAH box helicase, putative	—	OG6 TCSYLVIO_004479 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	Both
LmxM.31.2980 ⚠ ATP binding protein-like protein	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_004556	Both
LmxM.27.2200 ⚠ thioredoxin, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_004556	Both
LmxM.33.3080 exosome subunit rrp6p homologue, putative	—	OG6 TCSYLVIO_003804 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_004556	Both
LmxM.31.3460 ⚠ exosome-associated protein 2, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
LmxM.22.1580 ⚠ exosome complex exonuclease RRP45 homolog, pu	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
LmxM.11.0260 hypothetical protein, conserved	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_004556	Both
LmxM.23.1220 ⚠ T-complex protein 1, gamma subunit, putative	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
LmxM.31.1000 ⚠ chaperonin containing t-complex protein, puta	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
LmxM.03.0130 acetyltransferase, putative	—	OG6 TCSYLVIO_004519 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_004556	Both
LmxM.08_29.1460 hypothetical protein, conserved	—	OG6 TCSYLVIO_004312 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004312 ↔ TCSYLVIO_004556	Both
LmxM.27.0880 ⚠ 2-oxoglutarate dehydrogenase subunit, putativ	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005469 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005469	Both
LmxM.14.1140 hypothetical protein, conserved	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_010606 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010606	Both
LmxM.21.1700 ⚠ proteasome alpha 2 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	Both
LmxM.31.3270 ⚠ chaperonin alpha subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
LmxM.36.5390 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	Both
LmxM.34.3100 ⚠ ATP-dependent RNA helicase, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005835 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	Both
LmxM.34.4850 ⚠ proteasome alpha 1 subunit, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	Both

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