LmxM.33.0350

eukaryotic translation initiation factor 5, putative
Leishmania mexicana MHOM/GT/2001/U1103 OG6: OG6_101859 OG7: OG7_0007078 56 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 56 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmxM.13.1660 ⚠
chaperonin TCP20, putative
— OG7
LmxM.34.3840 ⚠
proteasome beta 2 subunit, putative
— Both
LmxM.32.1930 ⚠
phosphoribosyl transferase, putative, phospho
— Both
LmxM.36.3760 ⚠
60S ribosomal protein L10a, putative
— Both
LmxM.19.0295 ⚠
RNA binding protein
— Both
LmxM.34.2270
ATP-dependent RNA helicase-like protein
— OG6
LmxM.29.3040
eukaryotic translation initiation factor 3 su
— Both
LmxM.30.2970
acetyl-CoA carboxylase
— Both
LmxM.11.0240 ⚠
proteasome alpha 7 subunit, putative
— Both
LmxM.28.0110
proteasome beta 3 subunit, putative
— Both
LmxM.36.3000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmxM.36.6910 ⚠
T-complex protein 1, theta subunit, putative
— OG7
LmxM.27.1260 ⚠
T-complex protein 1, beta subunit, putative
— OG7
LmxM.34.3860 ⚠
T-complex protein 1, eta subunit, putative
— OG7
LmxM.36.3470 ⚠
2-oxoglutarate dehydrogenase E1 component, pu
— Both
LmxM.14.0310 ⚠
proteasome alpha 3 subunit, putative
— OG7
LmxM.10.0140 ⚠
DEAD/DEAH box helicase, putative, mitochondri
— OG7
LmxM.36.1600 ⚠
proteasome subunit alpha type-1, putative
— OG7
LmxM.08.0510 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
LmxM.31.0400 ⚠
ATP-dependent RNA helicase HEL67
— OG7
LmxM.36.2130 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LmxM.08.0080 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LmxM.27.0190 ⚠
proteasome alpha 7 subunit, putative
— OG7
LmxM.21.1830 ⚠
proteasome subunit alpha type-5, putative
— OG7
LmxM.28.2080 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
LmxM.19.0300 ⚠
RNA binding protein, putative
— OG7
LmxM.36.1650 ⚠
proteasome subunit beta type-5, putative
— OG7
LmxM.07.0340 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LmxM.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— Both
LmxM.33.2700
eukaryotic translation initiation factor 3 su
— OG6
LmxM.29.0570
spliceosome-associated protein, putative
— Both
LmxM.36.4910
hypothetical protein, conserved
— Both
LmxM.03.0690 ⚠
DEAD/DEAH box helicase, putative
— Both
LmxM.31.2980 ⚠
ATP binding protein-like protein
— Both
LmxM.27.2200 ⚠
thioredoxin, putative
— Both
LmxM.33.3080
exosome subunit rrp6p homologue, putative
— Both
LmxM.31.3460 ⚠
exosome-associated protein 2, putative
— Both
LmxM.22.1580 ⚠
exosome complex exonuclease RRP45 homolog, pu
— Both
LmxM.11.0260
hypothetical protein, conserved
— Both
LmxM.23.1220 ⚠
T-complex protein 1, gamma subunit, putative
— Both
LmxM.31.1000 ⚠
chaperonin containing t-complex protein, puta
— Both
LmxM.03.0130
acetyltransferase, putative
— Both
LmxM.08_29.1460
hypothetical protein, conserved
— Both
LmxM.27.0880 ⚠
2-oxoglutarate dehydrogenase subunit, putativ
— Both
LmxM.14.1140
hypothetical protein, conserved
— Both
LmxM.21.1700 ⚠
proteasome alpha 2 subunit, putative
— Both
LmxM.31.3270 ⚠
chaperonin alpha subunit, putative
— Both
LmxM.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— Both
LmxM.34.3100 ⚠
ATP-dependent RNA helicase, putative
— Both
LmxM.34.4850 ⚠
proteasome alpha 1 subunit, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.