TcCLB.505123.4

ATP-dependent RNA helicase, putative (fragment)
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_146508 OG7: OG7_0000698 23 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 23 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509805.210
hypothetical protein, conserved
— OG6
TcCLB.507809.110
WD domain, G-beta repeat, putative
— OG6
TcCLB.510101.250
hypothetical protein, conserved
— OG6
TcCLB.509805.130
bifunctional aminoacyl-tRNA synthetase, putat
— OG6
TcCLB.510101.210
PUB domain containing protein, putative
— OG6
TcCLB.509145.10
Ankyrin repeats (3 copies)/Zinc finger, C3HC4
— OG6
TcCLB.506375.80
hypothetical protein, conserved
— OG6
TcCLB.510323.10
protein kinase, putative
— OG6
TcCLB.503479.49
U6 snRNA-associated Sm-like protein LSm7p
— OG6
TcCLB.506755.279
hypothetical protein, conserved
— OG6
TcCLB.508647.40
replication factor C, subunit 1, putative
— OG6
TcCLB.509965.350
ubiquitin-protein ligase, putative
— OG6
TcCLB.509777.100
ubiquitin-activating enzyme, putative
— OG6
TcCLB.506135.70
hypothetical protein, conserved
— OG6
TcCLB.506885.380
hypothetical protein, conserved
— OG6
TcCLB.511577.50
endo-beta-N-acetylglucosaminidase, putative
— OG6
TcCLB.507711.320
DNA mismatch repair protein MSH2, putative
— OG6
TcCLB.508585.10
hypothetical protein, conserved
— OG6
TcCLB.510431.220
ribosome assembly protein RRB1, putative
— OG6
TcCLB.510741.40
hypothetical protein, conserved
— OG6
TcCLB.507747.220
protein farnesyltransferase, putative
— OG6
TcCLB.506457.130
Domain of unknown function (DUF4042), putativ
— OG6
TcCLB.506859.70
guide RNA associated protein, GAP2, putative
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.