TcCLB.506513.40

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_158023 OG7: OG7_0052097 49 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 49 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.510149.120 ⚠
flagellar radial spoke protein-like, putative
— OG7
TcCLB.507611.270 ⚠
hypothetical protein, conserved
— Both
TcCLB.506777.50 ⚠
cell cycle sequence binding phosphoprotein (R
— Both
TcCLB.508541.190 ⚠
cell cycle sequence binding phosphoprotein (R
— Both
TcCLB.506223.40 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcCLB.506239.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503905.50 ⚠
PSP1 C-terminal conserved region, putative
— OG7
TcCLB.510431.140 ⚠
dual specificity tyrosine-phosphorylation-reg
— OG7
TcCLB.480785.10 ⚠
serine/threonine kinase, putative, CMGC/DYRK
— OG7
TcCLB.506739.190 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcCLB.506519.60 ⚠
CMGC/CLK family protein kinase, putative
— OG7
TcCLB.508675.9 ⚠
CMGC/DYRK protein kinase, putative (fragment)
— OG7
TcCLB.427247.10 ⚠
CMGC/DYRK protein kinase, putative
— OG7
TcCLB.506755.240
hypothetical protein, conserved
— Both
TcCLB.511555.20
hypothetical protein, conserved
— OG7
TcCLB.511729.20 ⚠
hypothetical protein
— OG7
TcCLB.420989.10 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.509007.70 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506659.39 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.508347.40
hypothetical protein, conserved
— OG7
TcCLB.506925.150 ⚠
protein phosphatase 2C, putative
— OG7
TcCLB.506739.200 ⚠
pyruvate dehydrogenase phosphatase
— OG7
TcCLB.510609.110 ⚠
ATP-dependent RNA helicase, putative
— OG7
TcCLB.508723.100 ⚠
rab-like GTPase activating protein, putative
— OG7
TcCLB.506755.200 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508723.80 ⚠
disgorgin, putative
— Both
TcCLB.506755.190 ⚠
hypothetical protein, conserved
— Both
TcCLB.509979.40
Zn-finger in Ran binding protein and others/S
— Both
TcCLB.506895.30
Mitochondrial large ribosomal subunit mL85, p
— Both
TcCLB.506829.80
nicotinamidase, putative
— Both
TcCLB.506869.60 ⚠
protein kinase PK4, putative
— Both
TcCLB.509153.60
lipin, putative
— Both
TcCLB.504089.50 ⚠
Flagellar radial spoke protein 4/6
— Both
TcCLB.510513.50
hypothetical protein, conserved
— Both
TcCLB.503813.30 ⚠
hypothetical protein, conserved
— Both
TcCLB.509167.60 ⚠
Tumour suppressor, Mitostatin, putative
— Both
TcCLB.503989.60 ⚠
protein phosphatase 2C, putative (fragment)
— Both
TcCLB.503975.100
Present in the outer mitochondrial membrane p
— Both
TcCLB.510291.30 ⚠
protein phosphatase 2C-like, putative
— Both
TcCLB.504103.90 ⚠
PSP1 C-terminal conserved region, putative
— Both
TcCLB.506221.30 ⚠
protein phosphatase 2C, putative
— Both
TcCLB.508207.70 ⚠
Adenine phosphoribosyltransferase, putative
— Both
TcCLB.504147.150 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— Both
TcCLB.506963.110
NUDIX hydrolase 3, putative
— Both
TcCLB.511625.40 ⚠
protein phosphatase 2C, putative
— Both
TcCLB.509453.4 ⚠
hypothetical protein, conserved
— Both
TcCLB.508207.74 ⚠
Adenine phosphoribosyltransferase, putative
— Both
TcCLB.503981.20
hypothetical protein, conserved
— Both
TcCLB.511127.210
hypothetical protein, conserved
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.