TcIL3000_0_25410

ATPase family associated with various cellular activities (AAA), putative
Trypanosoma congolense IL3000 OG6: OG6_142131 OG7: OG7_0001167 138 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 138 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_3_3580 ⚠
nuclear transcription factor, putative
— OG7
TcIL3000_10_1050 ⚠
OB-fold nucleic acid binding domain/tRNA synt
— OG7
TcIL3000_3_2670 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_41150 ⚠
conserved protein
— OG7
TcIL3000_7_390 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_9_5670 ⚠
ubiquitin-protein ligase, putative (fragment)
— OG7
TcIL3000_6_1870 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000.11.12420 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
TcIL3000_0_31300 ⚠
co-chaperone GrpE, putative
— OG7
TcIL3000_0_55120 ⚠
hypothetical protein
— OG7
TcIL3000_0_11960 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
TcIL3000_0_55150 ⚠
ubiquitin-protein ligase, putative (fragment)
— OG7
TcIL3000_7_40 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_9230 ⚠
hypothetical protein
— OG7
TcIL3000_0_50370 ⚠
tubulin folding cofactor D, putative (fragmen
— OG7
TcIL3000.11.6000 ⚠
replication factor C, subunit 1, putative
— OG7
TcIL3000_6_3350 ⚠
replication factor C, subunit 2, putative
— OG7
TcIL3000_6_1570 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_9_3550 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_10910 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_4_2400 ⚠
eukaryotic translation initiation factor 2-al
— OG7
TcIL3000_0_47340 ⚠
protein kinase, putative
— OG7
TcIL3000.11.7780 ⚠
protein kinase, putative
— OG7
TcIL3000_5_3890 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcIL3000_9_1520 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcIL3000_0_31970 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000_0_04870 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000_5_2960 ⚠
Beta-lactamase superfamily domain containing
— OG7
TcIL3000_5_2330 ⚠
Centrosomal protein of 164 kDa, putative
— OG7
TcIL3000_0_24030 ⚠
WW domain containing protein, putative
— OG7
TcIL3000.11.12260 ⚠
WW domain containing protein, putative
— OG7
TcIL3000_0_54330 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.4300 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_1100 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_10_1090 ⚠
Domain of unknown function (DUF4042), putativ
— OG7
TcIL3000_0_13010 ⚠
WD domain, G-beta repeat, putative
— OG7
TcIL3000_3_1560 ⚠
ATP-dependent DEAD/H RNA helicase, putative (
— OG7
TcIL3000.11.2160 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
TcIL3000_0_08890 ⚠
inhibitor of serine peptidase (ISP), putative
— OG7
TcIL3000_0_08210 ⚠
ecotin, putative
— OG7
TcIL3000_0_25700 ⚠
inhibitor of serine peptidase (ISP), putative
— OG7
TcIL3000_5_1680 ⚠
Ecotin-like protein
— OG7
TcIL3000_0_30110 ⚠
WD domain, G-beta repeat, putative
— OG7
TcIL3000_0_21000 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_8_2730 ⚠
5'-3' exoribonuclease C, putative
— OG7
TcIL3000_10_13130 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_10_13140 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_8_2270 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.6870 ⚠
MRB1-associated protein
— OG7
TcIL3000_0_28240 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.