TcIL3000_10_2380

eukaryotic translation initiation factor 5, putative

Trypanosoma congolense IL3000 OG6: OG6_101859 OG7: OG7_0007078 66 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 66 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
TcIL3000_0_00860 ⚠ proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004556	Both
TcIL3000_8_1290 ⚠ hypothetical protein	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
TcIL3000_10_6410 ⚠ ATP-dependent DEAD/H RNA helicase, putative,	—	OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	OG7
TcIL3000.11.1600 ⚠ T-complex protein 1, beta subunit, putative (	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
TcIL3000_10_7080 ⚠ T-complex protein 1, theta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
TcIL3000_9_4650 ⚠ T-complex protein 1, eta subunit, putative, t	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
TcIL3000_0_41470 ⚠ T-complex protein 1, zeta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
TcIL3000.11.3010 ⚠ T-complex protein 1, zeta subunit, putative	—	OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	OG7
TcIL3000.11.7640 ⚠ proteasome alpha 7 subunit, putative	—	OG6 TCSYLVIO_001707 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	Both
TcIL3000_5_4040 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
TcIL3000_0_05230 ⚠ proteasome beta 3 subunit, putative	—	OG6 TCSYLVIO_001736 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001736 ↔ TCSYLVIO_004556	Both
TcIL3000_9_5840 helicase, putative	—	OG6 TCSYLVIO_001373 ↔ TCSYLVIO_004556	OG6
TcIL3000_0_19850 ⚠ acetyl-CoA carboxylase	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_004556	Both
TcIL3000_8_7160 ⚠ acetyl-CoA carboxylase	—	OG6 TCSYLVIO_002772 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_002772 ↔ TCSYLVIO_004556	Both
TcIL3000_6_3790 eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_003333 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003333 ↔ TCSYLVIO_004556	Both
TcIL3000.11.1340 ⚠ 2-oxoglutarate dehydrogenase subunit, putativ	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005469 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005469	Both
TcIL3000_10_4810 N-acetyltransferase subunit Nat1, putative	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_010020 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010020	Both
TcIL3000_10_8190 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	Both
TcIL3000_10_5710 ⚠ ATP-dependent RNA helicase DBP2A, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
TcIL3000_3_150 ⚠ proteasome alpha 7 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
TcIL3000_8_3710 ⚠ mitochondrial, ATP-dependent DEAD/H RNA helic	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
TcIL3000_10_90 ⚠ proteasome subunit alpha type-5, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
TcIL3000_0_04480 ⚠ ATP-dependent DEAD/H RNA helicase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
TcIL3000_10_12810 ⚠ RNA binding protein, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006059	OG7
TcIL3000_10_5090 ⚠ proteasome subunit alpha type-1, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
TcIL3000_10_5130 ⚠ proteasome subunit beta type-5, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005774 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_006999	OG7
TcIL3000.11.9180 ⚠ DEAD-box ATP-dependent RNA helicase, mitochon	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
TcIL3000_0_36040 ⚠ proteasome alpha 7 subunit	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
TcIL3000_5_3590 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	OG7
TcIL3000_0_60440 ⚠ ribose-phosphate pyrophosphokinase, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	OG7
TcIL3000_7_3640 ⚠ proteasome alpha 3 subunit, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	OG7
TcIL3000_8_1270 ⚠ ATP-dependent RNA helicase DBP2B, putative	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
TcIL3000_10_12440 ⚠ ATP-dependent RNA helicase HEL67	—	OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005835	OG7
TcIL3000.11.7580 hypothetical protein, conserved	—	OG6 TCSYLVIO_001704 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001704 ↔ TCSYLVIO_004556	Both
TcIL3000_9_3500 ⚠ proteasome alpha 1 subunit, putative, 20S pro	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005678 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_009369 OG7 TCSYLVIO_001707 ↔ TCSYLVIO_004556	Both
TcIL3000_10_2610 N-acetyltransferase, putative	—	OG6 TCSYLVIO_004519 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004519 ↔ TCSYLVIO_004556	Both
TcIL3000_6_210 ⚠ ribosomal RNA processing protein 45, putative	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
TcIL3000.11.16520 ⚠ exosome-associated protein 2	—	OG6 TCSYLVIO_001893 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_001893 ↔ TCSYLVIO_004556	Both
TcIL3000.11.14560 ⚠ T-complex protein 1, epsilon subunit, putativ	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
TcIL3000_8_3150 ⚠ T-complex protein 1, gamma subunit, putative	—	OG6 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000177 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_005312 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_008271	Both
TcIL3000_0_09310 ⚠ ribosomal RNA processing protein 6 (fragment)	—	OG6 TCSYLVIO_003804 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_004556	Both
TcIL3000_4_1200 ⚠ ribosomal RNA processing protein 6, putative	—	OG6 TCSYLVIO_003804 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003804 ↔ TCSYLVIO_004556	Both
TcIL3000.11.2790 ⚠ phosphoribosylpyrophosphate synthetase, putat	—	OG6 TCSYLVIO_004556 ↔ TCSYLVIO_004731 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_010787 OG7 TCSYLVIO_004556 ↔ TCSYLVIO_004731	Both
TcIL3000.11.16100 ⚠ ATP binding protein-like protein	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_004556	Both
TcIL3000_2_1050 ⚠ thioredoxin, putative	—	OG6 TCSYLVIO_000453 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_000453 ↔ TCSYLVIO_004556	Both
TcIL3000.11.11730 hypothetical protein, conserved	—	OG6 Tb927.10.2770 ↔ Tb927.11.11010 OG7 Tb927.10.2770 ↔ Tb927.11.11010	Both
TcIL3000_3_1560 ⚠ ATP-dependent DEAD/H RNA helicase, putative (	—	OG6 TCSYLVIO_004479 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	Both
TcIL3000_3_1550 ⚠ hypothetical protein	—	OG6 TCSYLVIO_004479 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_004479 ↔ TCSYLVIO_004556	Both
TcIL3000_6_1580 spliceosome-associated protein, putative	—	OG6 TCSYLVIO_003119 ↔ TCSYLVIO_004556 OG7 TCSYLVIO_003119 ↔ TCSYLVIO_004556	Both
TcIL3000_4_1640 eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_003837 ↔ TCSYLVIO_004556	OG6

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