TcIL3000_10_12440

ATP-dependent RNA helicase HEL67
Trypanosoma congolense IL3000 OG6: OG6_100461 OG7: OG7_0000120 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_9_1040 ⚠
U6 snRNA-associated Sm-like protein LSm6p, Sm
— OG7
TcIL3000_3_880 ⚠
U6 snRNA-associated Sm-like protein LSm8p
— OG7
TcIL3000_5_4560 ⚠
U6 snRNA-associated Sm-like protein LSm7p, pu
— OG7
TcIL3000_0_40190 ⚠
heat shock protein 70 (hsp70), putative
— OG6
TcIL3000_0_02950 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000_0_21650 ⚠
Hsp70 protein, putative (fragment)
— OG6
TcIL3000_4_490 ⚠
small nuclear ribonucleoprotein sm d3
— Both
TcIL3000_2_1520 ⚠
small nuclear ribonucleoprotein SmD2, putativ
— Both
TcIL3000_0_55930 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000_0_54460 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000_7_2270 ⚠
small nuclear ribonucleoprotein SmD1, SmD-1 l
— Both
TcIL3000_5_3200 ⚠
hypothetical protein, conserved
— Both
TcIL3000_2_890 ⚠
small nuclear ribonucleoprotein SmD1, putativ
— Both
TcIL3000.11.11990 ⚠
luminal binding protein 1 (BiP), putative
— OG6
TcIL3000.11.11940 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000.11.11810 ⚠
U5 snRNP-specific 40 kDa protein, putative
— Both
TcIL3000_5_2860 ⚠
Mitochondrial ATP synthase subunit, putative
— Both
TcIL3000.11.11980 ⚠
heat shock protein 70, putative
— OG6
TcIL3000_0_40210 ⚠
heat shock 70 kDa protein, putative (fragment
— OG6
TcIL3000_0_40200 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000_0_16980 ⚠
RNA editing exonuclease 2
— OG7
TcIL3000_7_780 ⚠
exonuclease, putative, RNA-editing complex pr
— OG7
TcIL3000_7_1780 ⚠
GTPase activating protein, putative
— OG7
TcIL3000_0_02810 ⚠
GTPase activating protein, putative (fragment
— OG7
TcIL3000_0_33930 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000_1_1040 ⚠
RNA-editing nuclease 1
— OG7
TcIL3000_0_54390 ⚠
hypothetical protein
— OG7
TcIL3000_0_48490 ⚠
Cupin-like domain containing protein, putativ
— OG7
TcIL3000_6_3790 ⚠
eukaryotic translation initiation factor 3 su
— OG7
TcIL3000_0_00970 ⚠
conserved protein, unknown function
— OG7
TcIL3000_0_57070 ⚠
conserved protein, unknown function
— OG7
TcIL3000_5_1490 ⚠
zinc finger CCCH domain containing protein 12
— OG7
TcIL3000_0_08320 ⚠
eukaryotic release factor 3, putative
— OG7
TcIL3000_3_50 ⚠
zinc finger protein 2, putative
— OG7
TcIL3000_9_4320 ⚠
elongation factor 1-alpha, putative
— OG7
TcIL3000_10_710 ⚠
hook complex protein, conserved (fragment)
— OG7
TcIL3000.11.6690 ⚠
eukaryotic release factor 3, putative
— OG7
TcIL3000_5_1510 ⚠
zinc finger CCCH domain containing protein 13
— OG7
TcIL3000_0_17500 ⚠
zinc finger CCCH domain containing protein 11
— OG7
TcIL3000_9_4330 ⚠
Elongation factor Tu GTP binding domain conta
— OG7
TcIL3000.11.2830 ⚠
ribosome assembly protein RRB1, putative
— OG7
TcIL3000_9_990 ⚠
endo-beta-N-acetylglucosaminidase, putative
— OG7
TcIL3000_0_49340 ⚠
zinc finger CCCH domain containing protein 13
— OG7
TcIL3000_10_1730 ⚠
elongation factor 1-alpha, putative (fragment
— OG7
TcIL3000_6_4390 ⚠
Zinc finger CCCH domain-containing protein 47
— OG7
TcIL3000_9_3760 ⚠
hypothetical protein
— OG7
TcIL3000_0_25090 ⚠
zinc finger CCCH domain containing protein 12
— OG7
TcIL3000_10_1740 ⚠
elongation factor 1-alpha, putative
— OG7
TcIL3000_0_37550 ⚠
zinc finger CCCH domain containing protein 11
— OG7
TcIL3000_9_6440 ⚠
U3 small nucleolar RNA-associated protein 6,
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.