TcIL3000_9_4550

PRP8 protein homologue (fragment)
Trypanosoma congolense IL3000 OG6: OG6_101765 OG7: OG7_0006744 70 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 70 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_5_2080 ⚠
ATP-dependent RNA helicase, putative (fragmen
— Both
TcIL3000.11.4440 ⚠
ATP-dependent RNA helicase, putative
— Both
TcIL3000_5_2070 ⚠
ATP-dependent RNA helicase, putative (fragmen
— Both
TcIL3000_8_3410 ⚠
DNA polymerase theta (helicase domain only),
— OG7
TcIL3000.11.14900 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TcIL3000.11.14890 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
TcIL3000_8_7160 ⚠
acetyl-CoA carboxylase
— Both
TcIL3000.11.14090 ⚠
U5 small nuclear ribonucleoprotein component,
— Both
TcIL3000_10_7550 ⚠
AAA domain containing protein, putative
— Both
TcIL3000_10_4520 ⚠
40S ribosomal protein S10, putative
— Both
TcIL3000_10_4510 ⚠
40S ribosomal protein S10, putative
— Both
TcIL3000.11.1850 ⚠
proteasome regulatory non-ATP-ase subunit 3,
— Both
TcIL3000_0_54950 ⚠
hypothetical protein (fragment)
— Both
TcIL3000_8_5000 ⚠
U6 snRNA-associated sm-like protein Lsm2
— Both
TcIL3000_2_240 ⚠
proteasome regulatory non-ATPase subunit 6
— Both
TcIL3000_3_880 ⚠
U6 snRNA-associated Sm-like protein LSm8p
— Both
TcIL3000_0_19850 ⚠
acetyl-CoA carboxylase
— Both
TcIL3000_2_1520 ⚠
small nuclear ribonucleoprotein SmD2, putativ
— Both
TcIL3000.11.3690 ⚠
proteasome regulatory ATPase subunit 2
— OG6
TcIL3000_2_890 ⚠
small nuclear ribonucleoprotein SmD1, putativ
— Both
TcIL3000_9_1390 ⚠
hypothetical protein, conserved
— Both
TcIL3000_10_2910 ⚠
serine peptidase, Clan SJ, family S16, putati
— OG6
TcIL3000_8_4600 ⚠
Putative snoRNA binding domain containing pro
— Both
TcIL3000_10_8610 ⚠
19S proteasome regulatory subunit, Regulatory
— OG6
TcIL3000.11.15690 ⚠
U5 snRNP-associated 102 kDa protein, putative
— Both
TcIL3000.11.15940 ⚠
proteasome regulatory non-ATP-ase subunit 7
— Both
TcIL3000_0_12400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
TcIL3000_0_42130 ⚠
hypothetical protein, conserved
— Both
TcIL3000.11.16170 ⚠
SPRY domain containing protein, putative (fra
— Both
TcIL3000.11.15510 ⚠
RNA-binding protein, putative
— Both
TcIL3000.11.12030 ⚠
receptor for activated C kinase 1
— OG7
TcIL3000_6_2360 ⚠
WD domain, G-beta repeat, putative
— OG7
TcIL3000_9_1040 ⚠
U6 snRNA-associated Sm-like protein LSm6p, Sm
— OG7
TcIL3000_5_4560 ⚠
U6 snRNA-associated Sm-like protein LSm7p, pu
— OG7
TcIL3000_10_4140 ⚠
small nuclear ribonucleoprotein, putative
— OG7
TcIL3000_3_1280 ⚠
translation elongation factor EF-2, putative
— OG7
TcIL3000_10_3760 ⚠
elongation factor 2, putative
— OG7
TcIL3000_0_54460 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000_8_40 ⚠
proteasome regulatory non-ATP-ase subunit 10,
— Both
TcIL3000_0_43330 ⚠
proteasome regulatory ATPase subunit 5
— OG6
TcIL3000_7_1890 ⚠
ATPase family associated with various cellula
— OG6
TcIL3000_0_40200 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000_0_40210 ⚠
heat shock 70 kDa protein, putative (fragment
— OG6
TcIL3000.11.11980 ⚠
heat shock protein 70, putative
— OG6
TcIL3000.11.11940 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000.11.11990 ⚠
luminal binding protein 1 (BiP), putative
— OG6
TcIL3000_10_13500 ⚠
proteasome regulatory non-ATP-ase subunit 9,
— Both
TcIL3000_0_55930 ⚠
heat shock 70 kDa protein, putative
— OG6
TcIL3000_0_21650 ⚠
Hsp70 protein, putative (fragment)
— OG6
TcIL3000_0_02950 ⚠
heat shock 70 kDa protein, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.