TcYC6_0112370

enolase
Trypanosoma cruzi Y C6 OG6: OG6_100260 OG7: OG7_0002539 46 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 46 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0112660 ⚠
CS domain containing protein, putative
— Both
TcYC6_0083800
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
TcYC6_0110480
C-8 sterol isomerase, putative
— Both
TcYC6_0115670
aconitase, putative
— Both
TcYC6_0175630
trypanothione reductase, putative
— Both
TcYC6_0060390 ⚠
glutamic--pyruvic transaminase, putative
— Both
TcYC6_0060380 ⚠
glutamic--pyruvic transaminase, putative
— Both
TcYC6_0111000
Serine/threonine-protein kinase NEK7, putativ
— OG6
TcYC6_0083700
transketolase, putative
— Both
TcYC6_0117150
gamma-glutamylcysteine synthetase, putative
— Both
TcYC6_0121550
2,3-bisphosphoglycerate-independent phosphogl
— Both
TcYC6_0126280
phosphomannomutase, putative
— Both
TcYC6_0080660 ⚠
elongation factor 2
— Both
TcYC6_0070940 ⚠
Co-chaperone protein P23
— Both
TcYC6_0045280
mercaptopyruvate sulfurtransferase, putative
— Both
TcYC6_0092460
SEP domain containing protein, putative
— Both
TcYC6_0017390
cytidine triphosphate synthase, putative
— Both
TcYC6_0099250 ⚠
putative nonspecific lipid-transfer protein
— OG7
TcYC6_0103660 ⚠
aminopeptidase
— OG7
TcYC6_0060080 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
TcYC6_0119810 ⚠
translation elongation factor EF-2, putative
— OG7
TcYC6_0102720 ⚠
aminopeptidase
— OG7
TcYC6_0051670 ⚠
small nuclear ribonucleoprotein component
— OG7
TcYC6_0110640 ⚠
Aminopeptidase M1, putative
— Both
TcYC6_0080650 ⚠
elongation factor 2
— Both
TcYC6_0069460
6-phosphogluconate dehydrogenase, decarboxyla
— Both
TcYC6_0069160
glycerol kinase, glycosomal, putative
— Both
TcYC6_0050610
Nucleoside diphosphate kinase 1
— Both
TcYC6_0066550 ⚠
aspartate carbamoyltransferase, putative
— Both
TcYC6_0042400
methylthioadenosine phosphorylase, putative
— Both
TcYC6_0074780 ⚠
isocitrate dehydrogenase, putative
— Both
TcYC6_0058320
asparagine synthetase a, putative
— Both
TcYC6_0110280 ⚠
Fumarate hydratase class I, cytosolic
— Both
TcYC6_0080630 ⚠
elongation factor 2
— Both
TcYC6_0063070 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
TcYC6_0115870
citrate synthase, putative
— Both
TcYC6_0080620 ⚠
elongation factor 2
— Both
TcYC6_0081680 ⚠
malic enzyme, putative
— Both
TcYC6_0081230 ⚠
fumarate hydratase, putative
— Both
TcYC6_0080640 ⚠
elongation factor 2
— Both
TcYC6_0054550 ⚠
aspartate carbamoyltransferase, putative
— Both
TcYC6_0031010 ⚠
3-ketoacyl-CoA thiolase, putative
— Both
TcYC6_0080670 ⚠
elongation factor 2
— Both
TcYC6_0086410
kynureninase, putative
— Both
TcYC6_0081690 ⚠
malic enzyme
— Both
TcYC6_0080610 ⚠
elongation factor 2
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.