TcYC6_0125930

aldehyde dehydrogenase
Trypanosoma cruzi Y C6 OG6: OG6_102015 OG7: OG7_0000704 24 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 24 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0047040 ⚠
NADH-dependent fumarate reductase
— Both
TcYC6_0098600 ⚠
glutamyl-tRNA synthetase, putative
— OG7
TcYC6_0011670 ⚠
protein phosphatase 2A, putative
— OG6
TcYC6_0050360 ⚠
protein phosphatase 4, putative
— OG6
TcYC6_0068780
acyl-CoA dehydrogenase, putative
— Both
TcYC6_0069340
cystathione gamma lyase, putative
— Both
TcYC6_0050370 ⚠
protein phosphatase 4, putative
— OG6
TcYC6_0000770
glucose-6-phosphate 1-dehydrogenase
— Both
TcYC6_0043280 ⚠
pyruvate phosphate dikinase, putative
— Both
TcYC6_0128180 ⚠
glutamine synthetase, putative
— Both
TcYC6_0007280
S-adenosylhomocysteine hydrolase, putative
— Both
TcYC6_0043290 ⚠
pyruvate phosphate dikinase, putative
— Both
TcYC6_0110280 ⚠
Fumarate hydratase class I, cytosolic
— Both
TcYC6_0046330 ⚠
glutamine synthetase, putative
— Both
TcYC6_0090540
aldose 1-epimerase, putative
— Both
TcYC6_0127080
inositol-3-phosphate synthase, putative
— Both
TcYC6_0028450 ⚠
glutaminyl-tRNA synthetase, putative
— Both
TcYC6_0032520
GDP-mannose pyrophosphorylase
— Both
TcYC6_0028640
putative glutamate dehydrogenase
— Both
TcYC6_0047490 ⚠
NADH-dependent fumarate reductase, putative
— Both
TcYC6_0072570
succinyl-coA:3-ketoacid-coenzyme A transferas
— Both
TcYC6_0047480 ⚠
NADH-dependent fumarate reductase
— Both
TcYC6_0074210
isovaleryl-coA dehydrogenase, putative
— Both
TcYC6_0081230 ⚠
fumarate hydratase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.