TvY486_1105630

malic enzyme, putative
Trypanosoma vivax Y486 OG6: OG6_100205 OG7: OG7_0002857 51 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 51 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TvY486_0904320 ⚠
Hsp70 protein, putative
— OG7
TvY486_0021490 ⚠
heat shock protein 70-related protein
— Both
TvY486_1112290 ⚠
heat shock protein 70, putative, (fragment)
— OG6
TvY486_0101720 ⚠
alanine aminotransferase, putative
— Both
TvY486_0801980 ⚠
acetyl-CoA synthetase, putative, (fragment)
— Both
TvY486_0043440 ⚠
hypothetical protein (fragment)
— Both
TvY486_0043450 ⚠
ABC transporter, putative (fragment)
— Both
TvY486_1007790 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
TvY486_0201160 ⚠
trypanothione synthetase (fragment)
— Both
TvY486_0903420 ⚠
hypothetical protein, conserved
— OG7
TvY486_0700860 ⚠
heat shock 70 kDa protein, putative
— OG7
TvY486_1106950 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
TvY486_0901560 ⚠
heat shock protein, putative
— OG7
TvY486_0806260 ⚠
guanine deaminase, putative
— Both
TvY486_0200790 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TvY486_1108110 ⚠
D-alanyl-glycyl endopeptidase, putative
— OG7
TvY486_0200780 ⚠
cysteine peptidase, Clan CA, family C51, puta
— OG7
TvY486_0303570 ⚠
paraflagellar rod protein, putative
— OG7
TvY486_0303580 ⚠
paraflagellar rod protein, putative
— OG7
TvY486_0026990 ⚠
hypothetical protein, conserved in T. vivax,
— OG7
TvY486_0303590 ⚠
paraflagellar rod protein, putative (fragment
— OG7
TvY486_0303560 ⚠
paraflagellar rod protein, putative (fragment
— OG7
TvY486_0301540 ⚠
translation elongation factor EF-2, putative
— OG7
TvY486_1116220 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TvY486_1003160 ⚠
ABC transporter protein, putative
— OG7
TvY486_1014910 ⚠
ABC transporter, putative
— OG7
TvY486_1007240 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— Both
TvY486_1013010 ⚠
citrate synthase, putative
— Both
TvY486_0905750 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— Both
TvY486_1105620 ⚠
malic enzyme, putative
— Both
TvY486_0803090 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— +2 more Both
TvY486_0303770 ⚠
Fumarate hydratase class I, cytosolic
— Both
TvY486_0301600 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
TvY486_1002920 ⚠
enolase, putative, (fragment)
— Both
TvY486_1002910 ⚠
enolase, putative
— Both
TvY486_0906720 ⚠
metallo-peptidase, Clan MG, Family M24, amino
— Both
TvY486_0201150 ⚠
paraflagellar rod protein 5, putative
— Both
TvY486_1004580 ⚠
elongation factor 2, putative, (fragment)
— Both
TvY486_1004590 ⚠
elongation factor 2, putative, (fragment)
— Both
TvY486_1100750 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— +2 more Both
TvY486_1013540 ⚠
aconitase, putative, (fragment), aconitase, (
— Both
TvY486_0014050 ⚠
heat shock protein 70, putative, (fragment)
— Both
TvY486_1108080 ⚠
cystathionine beta-synthase, putative
— OG6
TvY486_0037920 ⚠
heat shock 70 kDa protein, mitochondrial prec
— Both
TvY486_1112330 ⚠
heat shock protein 70, putative
— Both
TvY486_0905830 ⚠
Peroxin 19
— Both
TvY486_1113810 ⚠
Uncharacterised protein family (UPF0160), put
— Both
TvY486_0025780 ⚠
heat shock protein 70, putative (fragment)
— Both
TvY486_1102510 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
TvY486_0030700 ⚠
glucose-regulated protein 78, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.