LINF_180012200

citrate synthase - putative
Leishmania infantum JPCM5 OG6: OG6_101425 OG7: OG7_0003359 42 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 42 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_320031000 ⚠
NOL1/NOP2/sun family - putative
— Both
LINF_120011500 ⚠
alanine aminotransferase
— Both
LINF_300042700 ⚠
Protein of unknown function (DUF3808)/Tetratr
— Both
LINF_350011300 ⚠
hypothetical protein - conserved
— Both
LINF_310031700 ⚠
p-nitrophenylphosphatase - putative
— Both
LINF_200018100 ⚠
Nucleosome assembly protein (NAP) - putative
— Both
LINF_310031600 ⚠
p-nitrophenylphosphatase - putative
— Both
LINF_230010700 ⚠
acetyl-CoA synthetase - putative
— Both
LINF_360081700 ⚠
elks delta-like protein
— Both
LINF_290015200 ⚠
5-histidylcysteine sulfoxide synthase - putat
— Both
LINF_230014800 ⚠
acetyl-CoA synthetase - putative
— Both
LINF_340021300 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— Both
LINF_120010600 ⚠
glucose-6-phosphate isomerase
— Both
LINF_200011000 ⚠
cytidine triphosphate synthase - putative
— Both
LINF_180008800 ⚠
hypothetical protein - conserved
— Both
LINF_290027700 ⚠
NOL1/NOP2/sun family - putative
— OG7
LINF_280023700 ⚠
NOL1/NOP2/sun family - putative
— OG7
LINF_250021500 ⚠
PUA domain/NOL1/NOP2/sun family - putative
— OG7
LINF_310007000 ⚠
nucleolar protein - putative
— OG7
LINF_340022200 ⚠
Protein of unknown function (DUF3808) - putat
— OG7
LINF_260025300 ⚠
Methyltransferase domain containing protein -
— OG7
LINF_240012700 ⚠
malic enzyme - putative
— Both
LINF_350038800 ⚠
6-phosphogluconate dehydrogenase - decarboxyl
— Both
LINF_320036800 ⚠
nucleoside diphosphate kinase b
— Both
LINF_170008800 ⚠
cystathionine beta-synthase
— Both
LINF_350036100 ⚠
glycerol kinase - glycosomal - putative
— Both
LINF_260027800 ⚠
kynureninase - putative
— Both
LINF_160010500 ⚠
aspartate carbamoyltransferase - putative
— Both
LINF_240012800 ⚠
malic enzyme - putative
— Both
LINF_240007900 ⚠
fumarate hydratase - putative
— Both
LINF_050013500 ⚠
methylthioadenosine phosphorylase - putative
— Both
LINF_240027300 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase - put
— Both
LINF_100008300 ⚠
isocitrate dehydrogenase [NADP] - mitochondri
— Both
LINF_180010100 ⚠
aconitase - putative
— Both
LINF_290027200 ⚠
fumarate hydratase - putative
— Both
LINF_140018000 ⚠
enolase
— Both
LINF_300037500 ⚠
3-hydroxy-3-methylglutaryl-CoA reductase
— Both
LINF_320036700 ⚠
nucleoside diphosphate kinase b
— Both
LINF_360044500 ⚠
cysteine synthase
— OG6
LINF_140007600 ⚠
von Willebrand factor type A domain containin
— Both
LINF_340021100 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— Both
LINF_340021200 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.