LINF_240012800

malic enzyme - putative

Leishmania infantum JPCM5 OG6: OG6_100205 OG7: OG7_0002857 45 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 45 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LINF_110011900 ⚠ aminopeptidase - putative	—	OG7 TCSYLVIO_001500 ↔ TCSYLVIO_005560	OG7
LINF_290014000 ⚠ guanine deaminase - putative	—	OG6 TCSYLVIO_001501 ↔ TCSYLVIO_007737 OG7 TCSYLVIO_001501 ↔ TCSYLVIO_007737	Both
LINF_090014600 ⚠ Uncharacterised protein family (UPF0160) - p	—	OG6 TCSYLVIO_001501 ↔ TCSYLVIO_006555 OG7 TCSYLVIO_001501 ↔ TCSYLVIO_006555	Both
LINF_260013200 ⚠ aspartate--ammonia ligase - putative	—	OG6 TCSYLVIO_001501 ↔ TCSYLVIO_002332 OG7 TCSYLVIO_001501 ↔ TCSYLVIO_002332	Both
LINF_120011500 ⚠ alanine aminotransferase	—	OG6 Tb927.1.3950 ↔ Tb927.11.5450 OG6 Tb927.1.3950 ↔ Tb927.11.5440 OG7 Tb927.1.3950 ↔ Tb927.11.5450 OG7 Tb927.1.3950 ↔ Tb927.11.5440	Both
LINF_230010700 ⚠ acetyl-CoA synthetase - putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_001501 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_001501	Both
LINF_230014800 ⚠ acetyl-CoA synthetase - putative	—	OG6 TCSYLVIO_000046 ↔ TCSYLVIO_001501 OG7 TCSYLVIO_000046 ↔ TCSYLVIO_001501	Both
LINF_310039800 ⚠ phosphoglycan beta 1 -3 galactosyltransferase	—	OG6 LdBPK_240780.1 ↔ LdBPK_313210.1 OG7 LdBPK_240780.1 ↔ LdBPK_313210.1	Both
LINF_300021800 ⚠ hypothetical protein - conserved	—	OG6 LdBPK_240780.1 ↔ LdBPK_301690.1 OG7 LdBPK_240780.1 ↔ LdBPK_301690.1	Both
LINF_330008900 ⚠ ATP-binding cassette sub-family F member 1 -	—	OG6 LdBPK_240780.1 ↔ LdBPK_330340.1 OG7 LdBPK_240780.1 ↔ LdBPK_330340.1	Both
LINF_270025600 ⚠ trypanothione synthetase - putative	—	OG6 TCSYLVIO_000427 ↔ TCSYLVIO_001501 OG7 TCSYLVIO_000427 ↔ TCSYLVIO_001501	Both
LINF_360078300 ⚠ 2 -3-bisphosphoglycerate-independent phosphog	—	OG6 Tb927.10.7930 ↔ Tb927.11.5450 OG7 Tb927.10.7930 ↔ Tb927.11.5450	Both
LINF_360044500 ⚠ cysteine synthase	—	OG6 TCSYLVIO_001501 ↔ TCSYLVIO_008128 OG7 TCSYLVIO_001501 ↔ TCSYLVIO_008128	Both
LINF_110012000 ⚠ aminopeptidase - putative	—	OG7 TCSYLVIO_001500 ↔ TCSYLVIO_005560	OG7
LINF_330037900 ⚠ cysteine peptidase - Clan CA - family C51 - p	—	OG7 TCSYLVIO_000427 ↔ TCSYLVIO_001501	OG7
LINF_250031200 ⚠ CHAP domain/Glutathionylspermidine synthase p	—	OG7 TCSYLVIO_000427 ↔ TCSYLVIO_001501	OG7
LINF_230009800 ⚠ trypanothione synthetase - putative	—	OG7 TCSYLVIO_000427 ↔ TCSYLVIO_001501	OG7
LINF_330037600 ⚠ cysteine peptidase - Clan CA - family C51 - p	—	OG7 TCSYLVIO_000427 ↔ TCSYLVIO_001501	OG7
LINF_360065300 ⚠ aminopeptidase P1 - putative	—	OG7 TCSYLVIO_001380 ↔ TCSYLVIO_001501	OG7
LINF_250027700 ⚠ elongation factor 2-like protein	—	OG7 Tb927.10.4560 ↔ Tb927.11.5450 OG7 Tb927.10.4560 ↔ Tb927.11.5440	OG7
LINF_320028300 ⚠ U5 small nuclear ribonucleoprotein component	—	OG7 Tb927.10.4560 ↔ Tb927.11.5450 OG7 Tb927.10.4560 ↔ Tb927.11.5440	OG7
LINF_030006400 ⚠ ATP-binding cassette protein subfamily F - me	—	OG7 LdBPK_240780.1 ↔ LdBPK_330340.1	OG7
LINF_190012900 ⚠ ABC transport system ATP-binding protein - pu	—	OG7 LdBPK_240780.1 ↔ LdBPK_330340.1	OG7
LINF_270025400 ⚠ paraflagellar rod protein 5 - putative	—	OG6 TCSYLVIO_000425 ↔ TCSYLVIO_001501	OG6
LINF_350038800 ⚠ 6-phosphogluconate dehydrogenase - decarboxyl	—	OG6 Tb927.11.5440 ↔ Tb927.9.12110 OG6 Tb927.11.5450 ↔ Tb927.9.12110 OG7 Tb927.11.5440 ↔ Tb927.9.12110 OG7 Tb927.11.5450 ↔ Tb927.9.12110	Both
LINF_240007900 ⚠ fumarate hydratase - putative	—	OG6 Tb927.11.5440 ↔ Tb927.3.4500 OG6 Tb927.11.5050 ↔ Tb927.11.5440 OG7 Tb927.11.5440 ↔ Tb927.3.4500 OG7 Tb927.11.5050 ↔ Tb927.11.5440	Both
LINF_250028300 ⚠ succinyl-CoA synthetase alpha subunit - putat	—	OG6 Tb927.11.5450 ↔ Tb927.3.2230 OG7 Tb927.11.5450 ↔ Tb927.3.2230	Both
LINF_250028400 ⚠ succinyl-CoA synthetase alpha subunit - putat	—	OG6 Tb927.11.5450 ↔ Tb927.3.2230 OG7 Tb927.11.5450 ↔ Tb927.3.2230	Both
LINF_180012200 ⚠ citrate synthase - putative	—	OG6 Tb927.10.13430 ↔ Tb927.11.5450 OG6 Tb927.10.13430 ↔ Tb927.11.5440 OG7 Tb927.10.13430 ↔ Tb927.11.5450 OG7 Tb927.10.13430 ↔ Tb927.11.5440	Both
LINF_240012700 ⚠ malic enzyme - putative	—	OG6 Tb927.11.5440 ↔ Tb927.11.5450 OG7 Tb927.11.5440 ↔ Tb927.11.5450	Both
LINF_290027200 ⚠ fumarate hydratase - putative	—	OG6 Tb927.11.5440 ↔ Tb927.3.4500 OG6 Tb927.11.5050 ↔ Tb927.11.5440 OG7 Tb927.11.5440 ↔ Tb927.3.4500 OG7 Tb927.11.5050 ↔ Tb927.11.5440	Both
LINF_180012100 ⚠ citrate synthase - putative	—	OG6 Tb927.10.13430 ↔ Tb927.11.5450 OG6 Tb927.10.13430 ↔ Tb927.11.5440 OG7 Tb927.10.13430 ↔ Tb927.11.5450 OG7 Tb927.10.13430 ↔ Tb927.11.5440	Both
LINF_040015000 ⚠ hypothetical protein - conserved	—	OG6 LdBPK_041000.1 ↔ LdBPK_240780.1 OG7 LdBPK_041000.1 ↔ LdBPK_240780.1	Both
LINF_140018000 ⚠ enolase	—	OG6 Tb927.10.2890 ↔ Tb927.11.5450 OG6 Tb927.10.2890 ↔ Tb927.11.5440 OG7 Tb927.10.2890 ↔ Tb927.11.5450 OG7 Tb927.10.2890 ↔ Tb927.11.5440	Both
LINF_100008300 ⚠ isocitrate dehydrogenase [NADP] - mitochondri	—	OG6 Tb927.11.5440 ↔ Tb927.8.3690 OG6 Tb927.11.5440 ↔ Tb927.11.900 OG6 Tb927.11.5450 ↔ Tb927.11.900 OG7 Tb927.11.5440 ↔ Tb927.8.3690 +2 more	Both
LINF_350028800 ⚠ aminopeptidase P - putative	—	OG6 TCSYLVIO_001380 ↔ TCSYLVIO_001501 OG7 TCSYLVIO_001380 ↔ TCSYLVIO_001501	Both
LINF_360037500 ⚠ succinyl-CoA ligase [GDP-forming] beta-chain	—	OG6 Tb927.10.7410 ↔ Tb927.11.5450 OG7 Tb927.10.7410 ↔ Tb927.11.5450	Both
LINF_360007100 ⚠ elongation factor 2	—	OG6 Tb927.10.4560 ↔ Tb927.11.5450 OG6 Tb927.10.4560 ↔ Tb927.11.5440 OG7 Tb927.10.4560 ↔ Tb927.11.5450 OG7 Tb927.10.4560 ↔ Tb927.11.5440	Both
LINF_360006900 ⚠ elongation factor 2	—	OG6 Tb927.10.4560 ↔ Tb927.11.5450 OG6 Tb927.10.4560 ↔ Tb927.11.5440 OG7 Tb927.10.4560 ↔ Tb927.11.5450 OG7 Tb927.10.4560 ↔ Tb927.11.5440	Both
LINF_360006800 ⚠ elongation factor 2	—	OG6 Tb927.10.4560 ↔ Tb927.11.5450 OG6 Tb927.10.4560 ↔ Tb927.11.5440 OG7 Tb927.10.4560 ↔ Tb927.11.5450 OG7 Tb927.10.4560 ↔ Tb927.11.5440	Both
LINF_360007000 ⚠ elongation factor 2	—	OG6 Tb927.10.4560 ↔ Tb927.11.5450 OG6 Tb927.10.4560 ↔ Tb927.11.5440 OG7 Tb927.10.4560 ↔ Tb927.11.5450 OG7 Tb927.10.4560 ↔ Tb927.11.5440	Both
LINF_180010100 ⚠ aconitase - putative	—	OG6 Tb927.10.14000 ↔ Tb927.11.5450 OG6 Tb927.10.14000 ↔ Tb927.11.5440 OG7 Tb927.10.14000 ↔ Tb927.11.5450 OG7 Tb927.10.14000 ↔ Tb927.11.5440	Both
LINF_350038000 ⚠ Peroxin 19	—	OG6 TCSYLVIO_001500 ↔ TCSYLVIO_005818 OG7 TCSYLVIO_001500 ↔ TCSYLVIO_005818	Both
LINF_170008800 ⚠ cystathionine beta-synthase	—	OG6 TCSYLVIO_001501 ↔ TCSYLVIO_008128	OG6
LINF_330034900 ⚠ metallo-peptidase - Clan MF - Family M17	—	OG6 TCSYLVIO_001500 ↔ TCSYLVIO_005560 OG7 TCSYLVIO_001500 ↔ TCSYLVIO_005560	Both