LINF_270033000

WD-repeat protein
Leishmania infantum JPCM5 OG6: OG6_102145 OG7: OG7_0007160 97 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 97 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_360057700
WD domain - G-beta repeat - putative
— Both
LINF_150015800
hypothetical protein - conserved
— Both
LINF_350059500 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_300016500 ⚠
WW domain containing protein - putative
— OG7
LINF_340031100 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LINF_340029900 ⚠
Sec7 domain containing protein - putative
— OG7
LINF_050016100 ⚠
Phosphatidylinositol 4-phosphate 5-kinase - p
— OG7
LINF_090019500
AAA family ATPase - putative
— Both
LINF_270015100 ⚠
2-oxoglutarate dehydrogenase subunit - putati
— Both
LINF_360043300 ⚠
2-oxoglutarate dehydrogenase subunit - putati
— Both
LINF_060017400
hypothetical protein - conserved
— Both
LINF_120011300 ⚠
Tetratricopeptide repeat/TPR repeat - putativ
— Both
LINF_210008600
U1 small nuclear ribonucleoprotein C - putati
— Both
LINF_160017100 ⚠
WW domain containing protein - putative
— OG7
LINF_250025000
hypothetical protein - conserved
— Both
LINF_180015500
hypothetical protein - conserved
— Both
LINF_190011700 ⚠
kinesin - putative
— OG6
LINF_190011800 ⚠
kinesin - putative
— OG6
LINF_200016300 ⚠
phosphatidylinositol 3-kinase - putative
— Both
LINF_070008300
Paraflagellar rod protein - putative
— Both
LINF_040012000
Axonemal dynein light chain - putative
— Both
LINF_220022600
CCR4 associated factor - putative
— Both
LINF_270026800
small nuclear ribonucleoprotein protein - put
— Both
LINF_030014800 ⚠
MORN repeat - putative
— Both
LINF_190017000
hypothetical protein - conserved
— Both
LINF_320016400 ⚠
small nuclear ribonucleoprotein - putative
— OG7
LINF_080005000 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LINF_050009000 ⚠
structural maintenance of chromosome (SMC) -
— OG7
LINF_350040500 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LINF_340051500 ⚠
phosphatidylinositol 3-kinase (tor2) - putati
— OG7
LINF_360037400 ⚠
NUC194 domain/Phosphatidylinositol 3- and 4-k
— OG7
LINF_320020300 ⚠
phosphatidylinositol 3-related kinase - putat
— OG7
LINF_340047100 ⚠
target of rapamycin kinase 3
— OG7
LINF_020006200 ⚠
phosphatidylinositol kinase related protein -
— OG7
LINF_360073800 ⚠
target of rapamycin (TOR) kinase 1 - putative
— OG7
LINF_260005000 ⚠
Lsm7p protein - putative
— OG7
LINF_250023700 ⚠
LSM domain containing protein - putative
— OG7
LINF_300014700 ⚠
ubiquitin-protein ligase - putative
— OG7
LINF_010006500 ⚠
LSM domain containing protein - putative
— OG7
LINF_360010700 ⚠
U2 small nuclear ribonucleoprotein 16.5K - pu
— OG7
LINF_150006300 ⚠
zinc finger (CCCH type) protein - putative
— OG7
LINF_350014900 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LINF_130020100 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LINF_150006500 ⚠
zinc finger (CCCH type) protein - putative
— OG7
LINF_270006200 ⚠
hypothetical protein - conserved
— OG7
LINF_350015100 ⚠
Zinc finger C-x8-C-x5-C-x3-H type (and simila
— OG7
LINF_180013100 ⚠
DNA-directed RNA polymerase I subunit RPB5z -
— OG7
LINF_050009100 ⚠
Tetratricopeptide repeat/TPR repeat - putativ
— OG7
LINF_050006800
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— Both
LINF_300011700
Phosphoinositide-specific phospholipase C - e
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.