LPAL13_200007200

deoxyhypusine synthase

Leishmania panamensis MHOM/COL/81/L13 OG6: OG6_101093 OG7: OG7_0005231 133 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 133 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LPAL13_200051400 ⚠ deoxyhypusine synthase, putative	—	OG6 TCSYLVIO_004558 ↔ TCSYLVIO_007258 OG6 Tb927.1.870 ↔ Tb927.10.2750 OG7 Tb927.1.870 ↔ Tb927.10.2750 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007258	Both
LPAL13_210014900 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_003867 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007258	OG7
LPAL13_110012500 ⚠ Leucine Rich repeat, putative	—	OG6 TCSYLVIO_001642 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001642 ↔ TCSYLVIO_004558	Both
LPAL13_220008000 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001161 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001161 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001161 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001161 ↔ TCSYLVIO_007258	Both
LPAL13_300039000 ⚠ DNA ligase I, putative	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003375 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_007258	Both
LPAL13_300037600 ⚠ UV excision repair RAD23-like protein	—	OG6 TCSYLVIO_003361 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003361 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_007258	Both
LPAL13_180005200 ⚠ kinetoplast polyadenylation/uridylation facto	—	OG6 TCSYLVIO_000834 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_000834 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_007258	Both
LPAL13_090013200 ⚠ oligopeptidase b	—	OG6 TCSYLVIO_006546 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006546 ↔ TCSYLVIO_007258	Both
LPAL13_060008800 ⚠ serine peptidase, clan SC, family S9A-like pr	—	OG6 TCSYLVIO_006546 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_006546 ↔ TCSYLVIO_007258	Both
LPAL13_220010600 ⚠ Uncharacterised protein family UPF0066, putat	—	OG6 TCSYLVIO_001255 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001255 ↔ TCSYLVIO_007258	Both
LPAL13_220014600 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007258	Both
LPAL13_260017600 ⚠ Cupin-like domain containing protein, putativ	—	OG6 TCSYLVIO_002279 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002279 ↔ TCSYLVIO_004558	Both
LPAL13_290023500 ⚠ UDP-glucose:Glycoprotein Glucosyltransferase,	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_004363 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_007258	Both
LPAL13_270032300 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007258	OG6
LPAL13_350005400 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007258	OG6
LPAL13_220017900 ⚠ alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007258	Both
LPAL13_050012700 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007258	Both
LPAL13_280009900 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007258 +4 more	Both
LPAL13_320048400 ⚠ Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007258	Both
LPAL13_190005800 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
LPAL13_030013300 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007258	Both
LPAL13_000053700 ⚠ serine/threonine protein kinase sos2, putativ	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LPAL13_000039300 ⚠ serine/threonine kinase-like protein, putativ	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LPAL13_330025100 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LPAL13_070014900 ⚠ serine/threonine kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LPAL13_350015000 ⚠ SNF1-related protein kinases, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LPAL13_210006600 ⚠ serine/threonine-protein kinase-like protein	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LPAL13_280008700 ⚠ rrp44p homologue, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007258	OG7
LPAL13_280027500 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_004355 ↔ TCSYLVIO_004558	OG7
LPAL13_040008700 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_004558 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007258	OG7
LPAL13_200037300 ⚠ cleavage and polyadenylation specificity fact	—	OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_005414	OG7
LPAL13_330008100 ⚠ ATP-binding cassette sub-family F member 1, p	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
LPAL13_030006400 ⚠ ATP-binding cassette protein subfamily F, mem	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006012	OG7
LPAL13_350070800 ⚠ rab-like GTPase activating protein, putative	—	OG7 TCSYLVIO_004663 ↔ TCSYLVIO_007258 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_004663	OG7
LPAL13_300012600 ⚠ nuclear movement protein, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010327 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010327	OG7
LPAL13_160015700 ⚠ tyrosyl or methionyl-tRNA synthetase-like pro	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010624	OG7
LPAL13_300032400 ⚠ GTPase activator-like protein	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_008881	OG7
LPAL13_030010800 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_008932 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_008932 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007006 OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010148 +1 more	OG7
LPAL13_340048700 ⚠ predicted zinc finger protein	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LPAL13_200017000 ⚠ Dihydrouridine synthase (Dus), putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_009102	OG7
LPAL13_260019000 ⚠ MORN repeat/FYVE zinc finger containing prote	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LPAL13_150015100 ⚠ Rad9, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007065	OG7
LPAL13_310024900 ⚠ dihydrouridine synthase (Dus), putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_009102 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_009102	OG7
LPAL13_220009500 ⚠ Putative tRNA binding domain containing prote	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010624	OG7
LPAL13_330020900 ⚠ protein kinase, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_007401 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007401	OG7
LPAL13_340040100 ⚠ zinc finger protein, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LPAL13_230008600 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_010724 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_010724	OG7
LPAL13_190016400 ⚠ FYVE zinc finger containing protein, putative	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LPAL13_260017300 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_004558 ↔ TCSYLVIO_006188	OG7
LPAL13_000049800 ⚠ hypothetical protein	—	OG7 TCSYLVIO_007258 ↔ TCSYLVIO_007387 OG7 TCSYLVIO_004558 ↔ TCSYLVIO_007387	OG7

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