LTRL590_260007800

C-1-tetrahydrofolate synthase, cytoplasmic, putative
Leishmania tropica L590 OG6: OG6_100216 OG7: OG7_0002739 226 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 226 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LTRL590_310042000 ⚠
KH domain/Domain of unknown function (DUF1771
— Both
LTRL590_330037000 ⚠
transcription elongation factor-like protein
— Both
LTRL590_280005500 ⚠
hypothetical protein, conserved
— Both
LTRL590_050012700 ⚠
hypothetical protein, conserved
— OG6
LTRL590_270030800 ⚠
GTP binding protein, putative
— Both
LTRL590_160005400 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— Both
LTRL590_350013100 ⚠
aspartate aminotransferase, putative
— Both
LTRL590_240009000 ⚠
aspartate aminotransferase, putative
— Both
LTRL590_220016400 ⚠
translation initiation factor IF-2, putative
— OG6
LTRL590_220008300 ⚠
SEP domain containing protein, putative
— Both
LTRL590_230025900 ⚠
alanine racemase, putative
— Both
LTRL590_280017300 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LTRL590_280017000 ⚠
WD domain, G-beta repeat, putative
— Both
LTRL590_180005000 ⚠
kinetoplast polyadenylation/uridylation facto
— OG6
LTRL590_060014900 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG6
LTRL590_220008100 ⚠
hypothetical protein, conserved
— OG6
LTRL590_000028400 ⚠
calreticulin, putative
— OG6
LTRL590_310039000 ⚠
calreticulin, putative
— OG6
LTRL590_160013100 ⚠
transaldolase, putative
— Both
LTRL590_160013400 ⚠
Transaldolase, putative
— Both
LTRL590_220006100 ⚠
glutamine amidotransferase, putative
— Both
LTRL590_130015300 ⚠
leucyl-tRNA synthetase, putative
— OG6
LTRL590_110012300 ⚠
hypothetical protein, conserved
— OG6
LTRL590_260014700 ⚠
Glucosidase II beta subunit-like/Glucosidase
— OG6
LTRL590_110007200 ⚠
acidocalcisomal pyrophosphatase
— Both
LTRL590_140020800 ⚠
serine hydroxymethyltransferase (SHMT-L)
— OG6
LTRL590_250019500 ⚠
NPL4 family, putative
— Both
LTRL590_180011900 ⚠
serine/threonine kinase-like protein, putativ
— Both
LTRL590_200007700 ⚠
deoxyhypusine synthase, putative
— OG6
LTRL590_340043100 ⚠
hypothetical protein, conserved
— OG6
LTRL590_050008000 ⚠
monothiol glutaredoxin, putative
— Both
LTRL590_360079900 ⚠
hypothetical protein, conserved
— Both
LTRL590_290013600 ⚠
U-box domain protein, putative
— Both
LTRL590_250020500 ⚠
TAP42-like family, putative
— Both
LTRL590_250027400 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— Both
LTRL590_280031200 ⚠
serine hydroxymethyltransferase (SHMT-L)
— OG6
LTRL590_290020100 ⚠
carnitine/choline acetyltransferase, putative
— Both
LTRL590_030013100 ⚠
hypothetical protein, conserved
— Both
LTRL590_320027800 ⚠
Cytidylyltransferase, putative
— Both
LTRL590_320016000 ⚠
ubiquitin-conjugating enzyme protein, putativ
— Both
LTRL590_250028600 ⚠
hypothetical protein, conserved
— OG6
LTRL590_350017800 ⚠
monothiol glutaredoxin, putative
— Both
LTRL590_310024900 ⚠
diphthine synthase-like protein
— Both
LTRL590_350051600 ⚠
CS domain containing protein, putative
— Both
LTRL590_270018400 ⚠
WD domain, G-beta repeat, putative
— Both
LTRL590_340023100 ⚠
pyroglutamyl-peptidase I (C15 family)
— Both
LTRL590_330005900 ⚠
hypothetical protein, conserved
— Both
LTRL590_300039000 ⚠
valyl-tRNA synthetase, putative
— OG6
LTRL590_340043400 ⚠
phosphomannomutase-like protein
— Both
LTRL590_300015500 ⚠
conserved hypothetical protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.