LmjF.04.0500

Nucleotidyltransferase domain containing protein, putative
Leishmania major strain Friedlin OG6: OG6_479096 OG7: OG7_0003906 47 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 47 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmjF.35.0290 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.3430 ⚠
protein mkt1, putative
— OG7
LmjF.15.0640 ⚠
Galactose oxidase, central domain/Kelch motif
— OG7
LmjF.35.5090 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmjF.20.1480 ⚠
Myotubularin-related protein, putative
— OG7
LmjF.21.0820 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LmjF.19.0420 ⚠
DNA-directed RNA polymerase III subunit C11,
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.34.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmjF.26.0600 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.4145 ⚠
DNA-directed RNA polymerase I subunit, putati
— OG7
LmjF.31.1210 ⚠
Protein of unknown function (DUF3638)/Protein
— OG7
LmjF.22.1590 ⚠
hypothetical protein, conserved
— OG7
LmjF.20.1360 ⚠
exosome-associated protein 1, putative
— OG7
LmjF.03.0350 ⚠
protein kinase, putative
— OG7
LmjF.31.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmjF.16.1350 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
LmjF.34.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmjF.04.0120 ⚠
exosome complex exonuclease RRP40, putative
— OG7
LmjF.08.0550 ⚠
eukaryotic translation initiation factor 2 be
— OG7
LmjF.35.2250 ⚠
hypothetical protein, conserved
— Both
LmjF.32.2850 ⚠
CS domain/TPR repeat/Tetratricopeptide repeat
— Both
LmjF.34.2180 ⚠
hypothetical protein, conserved
— Both
LmjF.04.0890 ⚠
hypothetical protein, conserved
— Both
LmjF.33.1950 ⚠
hypothetical protein, conserved
— Both
LmjF.34.4090 ⚠
GRIP domain containing protein, putative
— Both
LmjF.06.0360 ⚠
hypothetical protein, conserved
— Both
LmjF.21.0610 ⚠
RNA helicase, putative
— Both
LmjF.13.0200 ⚠
Lipase (class 3), putative
— Both
LmjF.08.0420 ⚠
hypothetical protein, conserved
— Both
LmjF.12.0320 ⚠
Myotubularin-related protein, putative
— Both
LmjF.35.3470 ⚠
acyl transferase-like protein, putative
— Both
LmjF.31.1400 ⚠
hypothetical protein, conserved
— Both
LmjF.36.5700 ⚠
hypothetical protein, conserved
— Both
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— Both
LmjF.26.0730 ⚠
hypothetical protein, conserved
— Both
LmjF.07.0380 ⚠
RAVE protein 1 C terminal, putative
— OG7
LmjF.18.1240 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
LmjF.35.4330 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
LmjF.16.1550 ⚠
hypothetical protein, conserved
— OG7
LmjF.27.2170 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.5240 ⚠
glycosyl hydrolase, putative
— OG7
LmjF.28.0120 ⚠
DNA-direcetd RNA polymerase II, subunit 9, pu
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.