LmjF.32.2850

CS domain/TPR repeat/Tetratricopeptide repeat, putative
Leishmania major strain Friedlin OG6: OG6_105298 OG7: OG7_0010785 57 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 57 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.18.1240 ⚠
pre-RNA processing PIH1/Nop17, putative
— Both
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— Both
LmjF.34.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmjF.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmjF.35.4330 ⚠
pre-RNA processing PIH1/Nop17, putative
— OG7
LmjF.26.2370
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LmjF.25.0310
hypothetical protein, conserved
— Both
LmjF.30.3060
kinesin, putative
— OG6
LmjF.31.2640 ⚠
2-oxoglutarate dehydrogenase, e3 component, l
— Both
LmjF.31.1000
hypothetical protein, conserved
— Both
LmjF.30.1400 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.04.0500 ⚠
Nucleotidyltransferase domain containing prot
— Both
LmjF.29.1110
hypothetical protein, conserved
— Both
LmjF.15.0700
hypothetical protein, conserved
— Both
LmjF.25.1610
Eukaryotic translation initiation factor 3 su
— Both
LmjF.26.0730
hypothetical protein, conserved
— Both
LmjF.07.0700 ⚠
topoisomerase-related function protein-like p
— OG7
LmjF.33.0130
trans-splicing factor, putative
— Both
LmjF.36.0580 ⚠
hypothetical protein, unknown function
— OG7
LmjF.28.2740 ⚠
receptor for activated C kinase 1
— OG7
LmjF.28.2750 ⚠
receptor for activated C kinase 1
— OG7
LmjF.26.0490 ⚠
DNA polymerase sigma-like protein
— OG7
LmjF.29.1830 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LmjF.20.1480 ⚠
Myotubularin-related protein, putative
— OG7
LmjF.34.2520 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LmjF.07.0120 ⚠
Sec7 domain containing protein, putative
— OG7
LmjF.21.1120
U4/U6 small nuclear ribonuclear protein, puta
— OG6
LmjF.06.0360
hypothetical protein, conserved
— Both
LmjF.28.2620
Coatomer subunit gamma
— Both
LmjF.12.0320 ⚠
Myotubularin-related protein, putative
— Both
LmjF.04.0530
hypothetical protein, conserved
— Both
LmjF.30.3040
eukaryotic translation initiation factor 3 su
— Both
LmjF.31.1400
hypothetical protein, conserved
— Both
LmjF.04.0890
hypothetical protein, conserved
— Both
LmjF.33.0650
hypothetical protein, conserved
— Both
LmjF.13.0200
Lipase (class 3), putative
— Both
LmjF.14.0430
mRNA capping enzyme, beta chain, putative
— Both
LmjF.36.5240
glycosyl hydrolase, putative
— Both
LmjF.18.1480
NADH-ubiquinone oxidoreductase complex I subu
— Both
LmjF.14.0300
hypothetical protein, conserved
— Both
LmjF.21.0610
RNA helicase, putative
— Both
LmjF.31.2650 ⚠
acetoin dehydrogenase e3 component-like prote
— Both
LmjF.35.0610
hypothetical protein, conserved
— Both
LmjF.36.6980
eukaryotic translation initiation factor 3 su
— Both
LmjF.34.2450 ⚠
Sec7 domain containing protein, putative
— Both
LmjF.34.2180
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.