LmjF.30.3710

CPSF-domain protein, putative
Leishmania major strain Friedlin OG6: OG6_141915 OG7: OG7_0003450 91 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 91 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.31.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmjF.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmjF.32.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmjF.34.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmjF.21.1330 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LmjF.35.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmjF.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmjF.23.1380 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LmjF.32.1400 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LmjF.34.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmjF.33.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.36.1720 ⚠
neurobeachin/beige protein, putative
— OG7
LmjF.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmjF.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmjF.16.1220 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmjF.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmjF.36.2410 ⚠
Cullin protein neddylation domain containing
— OG7
LmjF.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmjF.36.3060 ⚠
cullin-like protein
— OG7
LmjF.29.0390 ⚠
RNA binding protein, putative
— OG7
LmjF.35.5040 ⚠
polyadenylate-binding protein 1
— OG7
LmjF.25.0080 ⚠
poly(A)-binding protein 3
— OG7
LmjF.35.4130 ⚠
polyadenylate-binding protein 2
— OG7
LmjF.35.3500 ⚠
zinc finger protein, putative
— OG7
LmjF.28.2570 ⚠
splicing factor 3B subunit 1, putative
— OG7
LmjF.30.0570 ⚠
spliceosome-associated protein, putative
— OG7
LmjF.36.3040 ⚠
pre-mRNA branch site protein p14, putative
— OG7
LmjF.30.1830 ⚠
splicing factor 3a, putative
— OG7
LmjF.36.2920 ⚠
PHF5-like protein, putative
— OG7
LmjF.02.0130 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmjF.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmjF.14.1170 ⚠
ras-like small GTPases, putative
— OG7
LmjF.35.4260 ⚠
predicted zinc finger protein
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.35.4090 ⚠
Splicing factor 3B subunit 10 (SF3b10), putat
— OG7
LmjF.11.0990 ⚠
adaptin-related protein-like protein
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— OG7
LmjF.16.0020 ⚠
adenylate kinase, putative
— OG7
LmjF.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmjF.04.0960 ⚠
UMP/CMP kinase, putative
— OG7
LmjF.06.0500 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.36.1360 ⚠
adenylate kinase, putative
— OG7
LmjF.36.6770 ⚠
beta adaptin, putative
— OG7
LmjF.35.2490 ⚠
hypothetical protein, conserved
— Both
LmjF.34.2790 ⚠
hypothetical protein, conserved
— Both
LmjF.18.0830 ⚠
Periodic tryptophan protein 2 homolog, putati
— Both
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.