LmjF.36.6310

homocysteine S-methyltransferase, putative
Leishmania major strain Friedlin OG6: OG6_102920 OG7: OG7_0003584 54 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 54 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.06.0220 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.2770
mucin-like protein, putative
— Both
LmjF.35.3890
calmodulin-like protein
— OG6
LmjF.36.6020
OTU-like cysteine protease, putative
— Both
LmjF.30.1240 ⚠
calcium-binding protein, putative
— OG7
LmjF.24.1750 ⚠
SET domain containing protein, putative
— OG7
LmjF.23.0790 ⚠
SET domain containing protein, putative
— OG7
LmjF.34.1050 ⚠
TPR repeat/SET domain containing protein, put
— OG7
LmjF.27.0160 ⚠
SET domain containing protein, putative
— OG7
LmjF.08.0880 ⚠
SET domain containing protein, putative
— OG7
LmjF.19.0340 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.0510 ⚠
SET domain containing protein, putative
— OG7
LmjF.06.1000 ⚠
SET domain containing protein, putative
— OG7
LmjF.12.1300 ⚠
SET domain containing protein, putative
— OG7
LmjF.36.6080 ⚠
rab-like GTPase activating protein, putative
— Both
LmjF.36.3120 ⚠
hypothetical protein, conserved
— OG7
LmjF.31.2500 ⚠
ferredoxin, 2fe-2s-like protein
— OG7
LmjF.31.2510 ⚠
ferredoxin, 2fe-2s-like protein
— OG7
LmjF.31.0255 ⚠
hypothetical protein, conserved
— OG7
LmjF.17.1210 ⚠
MSP (Major sperm protein) domain containing p
— OG7
LmjF.36.6070 ⚠
disgorgin, putative
— OG7
LmjF.28.1340 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LmjF.12.0190 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.28.1350 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.28.1380 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.35.2410 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.32.2910 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.36.6180 ⚠
Sucrase/ferredoxin-like, putative
— Both
LmjF.31.2490 ⚠
ferredoxin, 2fe-2s-like protein
— Both
LmjF.26.1050 ⚠
2Fe-2S iron-sulfur cluster binding domain con
— Both
LmjF.31.2480 ⚠
ferredoxin 2fe-2s-like protein
— Both
LmjF.09.0470 ⚠
kinetoplastid-specific phospho-protein phosph
— OG6
LmjF.05.0100 ⚠
kinetoplastid-specific phospho-protein phosph
— OG6
LmjF.12.0020
PITH domain-containing protein
— Both
LmjF.35.0990
hypothetical protein, conserved
— Both
LmjF.23.0010
hypothetical protein, conserved
— Both
LmjF.34.3360
D-Tyr-tRNA(Tyr) deacylase, putative
— Both
LmjF.20.1060
hypothetical protein, unknown function
— Both
LmjF.28.1370 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LmjF.16.1480
hypothetical protein, conserved
— Both
LmjF.32.1870
Cation efflux family, putative
— Both
LmjF.29.2210
leucine-rich repeat-containing protein
— Both
LmjF.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
LmjF.34.1155
Uncharacterised ACR, YggU family COG1872, put
— Both
LmjF.30.0370
mitogen-activated protein kinase 12, putative
— OG6
LmjF.12.0280
ornithine decarboxylase, putative
— Both
LmjF.34.2950 ⚠
EF-hand domain pair, putative
— Both
LmjF.23.0820 ⚠
SET domain containing protein, putative
— Both
LmjF.35.5260
hypothetical protein, conserved
— Both
LmjF.35.3010
trypanothione-dependent glyoxalase I
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.