TcCLB.506885.290

DNA replication licensing factor MCM9, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_104298 OG7: OG7_0001163 107 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 107 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.506933.40 ⚠
DNA replication licensing factor MCM2, putati
— +17 more OG7
TcCLB.511127.140 ⚠
DNA replication licensing factor MCM4, putati
— +17 more OG7
TcCLB.503425.29 ⚠
DNA replication licensing factor MCM8, putati
— +17 more OG7
TcCLB.511109.100 ⚠
DNA replication licensing factor MCM3, putati
— +17 more OG7
TcCLB.509069.49 ⚠
DNA replication licensing factor MCM7, putati
— +17 more OG7
TcCLB.507527.30 ⚠
DNA replication licensing factor MCM6, putati
— +17 more OG7
TcCLB.508647.140 ⚠
DNA replication licensing factor MCM5, putati
— +17 more OG7
TcCLB.508921.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509453.10 ⚠
PRP38 family, putative
— OG7
TcCLB.504149.50 ⚠
hypothetical protein, conserved
— OG7
TcCLB.507641.14 ⚠
neurobeachin/beige protein, putative
— OG7
TcCLB.509011.20 ⚠
RNA polymerase IIA largest subunit, putative
— OG7
TcCLB.511113.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.506949.10 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.511071.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508239.30 ⚠
neurobeachin/beige-like protein, putative
— OG7
TcCLB.403789.9 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
TcCLB.507639.110 ⚠
hypothetical protein, conserved
— OG7
TcCLB.443683.9 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.511115.10 ⚠
hypothetical protein, conserved
— OG7
TcCLB.504119.4 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
TcCLB.401473.9 ⚠
DNA-directed RNA polymerase I largest subunit
— OG7
TcCLB.508839.89 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
TcCLB.506357.140 ⚠
Periodic tryptophan protein 2 homolog, putati
— OG7
TcCLB.503619.39 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506775.60 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503529.10 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.414517.9 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcCLB.508277.70 ⚠
DNA replication complex GINS protein PSF1
— OG7
TcCLB.510325.50 ⚠
DNA replication complex GINS protein SLD5, pu
— +2 more OG7
TcCLB.508207.80 ⚠
Mini-chromosome maintenance complex-binding p
— +1 more OG7
TcCLB.507483.80 ⚠
O-phosphoseryl-tRNA(Sec) selenium transferase
— OG7
TcCLB.447255.4 ⚠
ubiquitin, putative
— OG7
TcCLB.506773.130 ⚠
pumilio-repeat, RNA-binding protein, putative
— OG7
TcCLB.504033.180 ⚠
hypothetical protein, conserved
— OG7
TcCLB.503971.10 ⚠
2OG-Fe(II) oxygenase superfamily, putative
— OG7
TcCLB.510773.9 ⚠
Thioredoxin-like/Protein of unknown function
— OG7
TcCLB.511545.100 ⚠
RNA methyltransferase, putative
— OG7
TcCLB.509067.40 ⚠
NADH dehydrogenase subunit NI8M, putative
— OG7
TcCLB.506673.60 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
TcCLB.510771.9 ⚠
Thioredoxin-like/Protein of unknown function
— OG7
TcCLB.510101.150 ⚠
adaptin-related protein-like, putative
— OG7
TcCLB.506527.4 ⚠
Flagellum attachment zone protein 9 (fragment
— OG7
TcCLB.506633.100 ⚠
hypothetical protein, conserved
— OG7
TcCLB.506525.162 ⚠
Flagellum attachment zone protein 9 (fragment
— OG7
TcCLB.510089.50 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
TcCLB.510409.39 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
TcCLB.503813.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509199.40 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508209.70 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.