TcCLB.511543.40

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_147027 OG7: OG7_0043065 24 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 24 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.508569.130 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
TcCLB.507521.10
hypothetical protein, conserved
— OG7
TcCLB.508207.230 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
TcCLB.510963.50 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
TcCLB.503579.110 ⚠
pseudouridylate synthase I, putative
— OG7
TcCLB.511751.180 ⚠
pseudouridine synthase A-like protein, putati
— OG7
TcCLB.511801.10 ⚠
leucine rich repeat
— OG7
TcCLB.509757.20 ⚠
leucine carboxyl methyltransferase, putative
— OG7
TcCLB.507669.14 ⚠
hypothetical protein, conserved
— OG7
TcCLB.449247.20 ⚠
hypothetical protein, conserved
— OG7
TcCLB.508205.4 ⚠
hypothetical protein, conserved
— OG7
TcCLB.509099.150
cdc2-related kinase 9
— OG6
TcCLB.507711.160
hypothetical protein, conserved
— Both
TcCLB.508181.20 ⚠
6-phosphofructo-2-kinase 1
— Both
TcCLB.506777.60
NGG1 interacting factor 3, putative
— Both
TcCLB.507099.70
hypothetical protein, conserved
— Both
TcCLB.508813.50
oxidoreductase-like protein, putative
— Both
TcCLB.506773.80
hypothetical protein, conserved
— Both
TcCLB.507511.40
G5-interacting protein, putative
— Both
TcCLB.503959.50 ⚠
hypothetical protein, conserved
— Both
TcCLB.506483.10
Triglyceride lipase, putative
— OG6
TcCLB.511743.20
hypothetical protein, conserved
— Both
TcCLB.510963.39
PUB domain containing protein, putative
— Both
TcCLB.508463.29 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.