TcIL3000_6_3840

homoserine kinase
Trypanosoma congolense IL3000 OG6: OG6_103889 OG7: OG7_0009339 76 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 76 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_10_3760 ⚠
elongation factor 2, putative
— OG7
TcIL3000_0_04870 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000_10_8600 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_7_5350 ⚠
tRNA-dihydrouridine synthase 3, putative
— OG7
TcIL3000.11.14630 ⚠
Zinc finger, ZZ type, putative
— OG7
TcIL3000_10_4060 ⚠
tRNA-dihydrouridine synthase 2, putative
— OG7
TcIL3000_0_42020 ⚠
zinc carboxypeptidase, putative
— OG7
TcIL3000_6_3140 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_0_14160 ⚠
dihydrouridine synthase (Dus), putative (frag
— OG7
TcIL3000_0_19090 ⚠
hypothetical protein
— OG7
TcIL3000.11.10800 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcIL3000.11.14090 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
TcIL3000_10_8960
iron-containing hydrogenase, putative
— Both
TcIL3000_8_3320 ⚠
Beta-lactamase superfamily domain containing
— Both
TcIL3000_7_2330 ⚠
Beta-lactamase superfamily domain containing
— Both
TcIL3000.11.9490
Replication factor A protein 1
— Both
TcIL3000.11.15240
small GTPase
— OG6
TcIL3000_10_1320
ras-related protein Rab21, putative
— OG6
TcIL3000_8_1600
phosphotyrosyl phosphate activator protein, p
— Both
TcIL3000_5_4340 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
TcIL3000_3_2470
hypothetical protein, conserved
— OG7
TcIL3000_0_26670 ⚠
p22 protein precursor, putative
— OG7
TcIL3000_7_5760 ⚠
mitochondrial glycoprotein-like protein, puta
— OG7
TcIL3000_0_19760 ⚠
Ankyrin repeats (3 copies)/Zinc finger, C3HC4
— OG7
TcIL3000_8_4400 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
TcIL3000_8_3530 ⚠
Zinc finger, C3HC4 type (RING finger) contain
— OG7
TcIL3000_0_20330 ⚠
Plus-3 domain/Zinc finger, C3HC4 type (RING f
— OG7
TcIL3000_0_24910 ⚠
Plus-3 domain/Zinc finger, C3HC4 type (RING f
— OG7
TcIL3000_5_4320 ⚠
XRN 5'-3' exonuclease N-terminus, putative (f
— OG7
TcIL3000_2_220
casein kinase II, alpha chain
— OG6
TcIL3000_7_6070 ⚠
GTP-binding protein, putative
— OG7
TcIL3000.11.2390 ⚠
GTP-binding protein, putative
— OG7
TcIL3000_7_270 ⚠
GTP-binding protein, putative
— OG7
TcIL3000_9_3230 ⚠
GTP-binding protein, putative
— OG7
TcIL3000_0_31970 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
TcIL3000_4_2920 ⚠
tRNA-dihydrouridine synthase 4, putative
— OG7
TcIL3000_0_55150 ⚠
ubiquitin-protein ligase, putative (fragment)
— OG7
TcIL3000_10_9050 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
TcIL3000_2_370 ⚠
serine peptidase, putative, ATP-dependent Clp
— Both
TcIL3000_0_02990 ⚠
Tubulin/FtsZ family, putative
— Both
TcIL3000_1_890 ⚠
Tubulin/FtsZ family, putative
— Both
TcIL3000_7_4940
mercaptopyruvate sulfurtransferase, putative
— Both
TcIL3000_0_55160 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcIL3000_8_2480 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcIL3000_0_52490
Vta1 like, putative
— Both
TcIL3000_8_1790
pitrilysin-like metalloprotease, putative, me
— Both
TcIL3000_6_1930 ⚠
p22 protein precursor, putative
— Both
TcIL3000_0_53490 ⚠
p22 protein precursor
— Both
TcIL3000_8_7090 ⚠
peptidase, putative
— Both
TcIL3000_2_1650 ⚠
chaperone protein ClpB1, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.