C4B63_26g201

cAMP specific phosphodiesterase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100960 OG7: OG7_0000695 46 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 46 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_9g267 ⚠
paraflagellar rod protein 5
— OG7
C4B63_168g17 ⚠
conserved hypothetical protein
— Both
C4B63_102g62 ⚠
conserved hypothetical protein
— Both
C4B63_22g161 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_27g180 ⚠
ATP-dependent protease ATPase subunit HslU2
— Both
C4B63_23g242 ⚠
radial spoke protein RSP10
— OG7
C4B63_24g1533c ⚠
conserved hypothetical protein
— OG7
C4B63_32g1409c ⚠
cysteine peptidase inhibitor (Chagasin)
— OG7
C4B63_187g86c ⚠
cysteine peptidase inhibitor
— OG7
C4B63_10g287 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_10g288 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_10g290 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_59g115 ⚠
stress-inducible protein STI1-like(fragment)
— OG6
C4B63_10g289 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_9g266 ⚠
paraflagellar rod protein 5
— OG7
C4B63_10g291 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_83g33 ⚠
conserved hypothetical protein
— OG7
C4B63_25g189 ⚠
3'5'-cyclic nucleotide phosphodiesterase
— OG7
C4B63_23g195 ⚠
3', 5'-cyclic nucleotide phosphodiesterase
— OG7
C4B63_4g243 ⚠
cAMP phosphodiesterase A
— OG7
C4B63_23g223 ⚠
cyclic nucleotide phosphodiesterase
— OG7
C4B63_10g450 ⚠
flagellar radial spoke protein-like
— OG7
C4B63_83g29 ⚠
ATP-dependent protease ATPase subunit HslU1
— OG7
C4B63_51g174 ⚠
Flagellar radial spoke protein 4/6
— Both
C4B63_170g28 ⚠
adenylosuccinate synthetase
— Both
C4B63_2g566 ⚠
phenylalanyl-tRNA synthetase
— Both
C4B63_27g222 ⚠
leucine-rich repeat protein(fragment)
— Both
C4B63_27g221 ⚠
leucine-rich repeat protein
— Both
C4B63_18g220 ⚠
kinesin
— OG6
C4B63_25g288 ⚠
inosine-guanine nucleoside hydrolase
— Both
C4B63_26g199 ⚠
cAMP specific phosphodiesterase
— Both
C4B63_26g198 ⚠
cAMP specific phosphodiesterase
— Both
C4B63_348g24 ⚠
guanine deaminase
— Both
C4B63_10g404 ⚠
guanine deaminase
— Both
C4B63_11g32 ⚠
conserved hypothetical protein
— Both
C4B63_46g82 ⚠
adenylosuccinate synthetase
— Both
C4B63_33g8 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— Both
C4B63_29g3 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— Both
C4B63_56g104 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— Both
C4B63_28g27 ⚠
clathrin coat assembly protein
— Both
C4B63_4g146 ⚠
pyruvate kinase 2
— Both
C4B63_227g20 ⚠
pyruvate kinase 2
— Both
C4B63_47g83 ⚠
nuclear cap binding complex subunit CBP110
— Both
C4B63_38g169 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_21g86 ⚠
conserved hypothetical protein
— Both
C4B63_22g164 ⚠
calpain-like cysteine peptidase
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.