C4B63_18g220

kinesin
Trypanosoma cruzi Dm28c 2018 OG6: OG6_145418 OG7: OG7_0000136 92 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 92 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_20g353 ⚠
myosin IB heavy chain
— OG6
C4B63_286g18 ⚠
eukaryotic translation initiation factor 3 su
— OG6
C4B63_7g68 ⚠
Brefeldin A-inhibited guanine nucleotide-exch
— OG6
C4B63_7g67 ⚠
Sec7 guanine-nucleotide exchange factor
— OG6
C4B63_7g421
coatomer alpha subunit
— OG6
C4B63_63g7 ⚠
eukaryotic translation initiation factor 3 su
— OG6
C4B63_80g31
Dynein assembly factor 4, axonemal
— OG6
C4B63_76g58 ⚠
Tripartite attachment complex protein 102
— OG6
C4B63_9g306
dynein intermediate chain
— OG6
C4B63_76g57 ⚠
Tripartite attachment complex protein 102
— OG6
C4B63_20g352 ⚠
myosin IB heavy chain
— OG6
C4B63_268g22 ⚠
myosin IB heavy chain
— OG6
C4B63_33g8 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— OG6
C4B63_268g21 ⚠
myosin IB heavy chain
— OG6
C4B63_20g322
conserved hypothetical protein
— OG6
C4B63_51g174
Flagellar radial spoke protein 4/6
— OG6
C4B63_16g21 ⚠
conserved hypothetical protein
— OG6
C4B63_16g20 ⚠
conserved hypothetical protein
— OG6
C4B63_16g22 ⚠
conserved hypothetical protein
— OG6
C4B63_12g237
eukaryotic release factor 3
— OG6
C4B63_18g223
eukaryotic translation initiation factor 3 su
— OG6
C4B63_52g137
conserved hypothetical protein
— OG6
C4B63_6g279 ⚠
Coatomer subunit gamma
— OG6
C4B63_37g159 ⚠
mucin TcMUCII
— OG6
C4B63_11g83
Eukaryotic translation initiation factor 3 su
— OG6
C4B63_37g373 ⚠
ribosome biogenesis protein
— OG6
C4B63_24g273 ⚠
Probable E3 ubiquitin-protein ligase HERC1
— OG6
C4B63_62g90 ⚠
ribosome biogenesis protein
— OG6
C4B63_24g272 ⚠
Zn-finger in Ran binding protein and others/S
— OG6
C4B63_6g119
oxidoreductase-like protein
— OG6
C4B63_21g277
conserved hypothetical protein
— OG6
C4B63_30g226 ⚠
lipin
— OG6
C4B63_30g227 ⚠
lipin
— OG6
C4B63_39g160 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_52g168 ⚠
Cilia- and flagella-associated protein 44
— OG6
C4B63_22g161 ⚠
calpain-like cysteine peptidase
— OG6
C4B63_386g19 ⚠
mucin TcMUCII
— OG6
C4B63_71g85 ⚠
mucin TcMUCII
— OG6
C4B63_71g5 ⚠
mucin TcMUCII
— OG6
C4B63_9g249 ⚠
conserved hypothetical protein
— OG6
C4B63_9g250 ⚠
Dpy-30 motif containing protein
— OG6
C4B63_71g164 ⚠
mucin TcMUCII
— OG6
C4B63_10g126
conserved hypothetical protein
— OG6
C4B63_28g27
clathrin coat assembly protein
— OG6
C4B63_56g104 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— OG6
C4B63_29g3 ⚠
Phosphatidylinositol 4-phosphate 5-kinase
— OG6
C4B63_2g509 ⚠
arginyl-tRNA synthetase
— OG6
C4B63_4g320
conserved hypothetical protein
— OG6
C4B63_4g228
conserved hypothetical protein
— OG6
C4B63_69g26
endo-beta-N-acetylglucosaminidase
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.