C4B63_2g509

arginyl-tRNA synthetase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100350 OG7: OG7_0003615 77 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 77 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_42g42 ⚠
co-chaperone GrpE
— Both
C4B63_17g278 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_7g380 ⚠
phosphatidylinositol 3-kinase(fragment)
— OG7
C4B63_124g3 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_34g361 ⚠
phosphatidylinositol kinase related protein
— OG7
C4B63_124g2 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_22g113 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_72g106 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_276g11 ⚠
DIS3-like exonuclease(fragment)
— OG7
C4B63_30g129 ⚠
rrp44p homologue
— OG7
C4B63_17g277 ⚠
phosphatidylinositol 3-related kinase
— OG7
C4B63_168g16 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_42g203 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_42g202 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_102g61 ⚠
aspartyl-tRNA synthetase
— Both
C4B63_14g96 ⚠
isoleucil-tRNA synthetase
— Both
C4B63_14g97 ⚠
isoleucyl-tRNA synthetase
— Both
C4B63_6g521 ⚠
DIS3-like exonuclease
— Both
C4B63_81g44 ⚠
tRNA (cytosine(34)-C(5))-methyltransferase
— Both
C4B63_23g207 ⚠
tRNA (cytosine(34)-C(5))-methyltransferase
— Both
C4B63_10g291 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_42g172 ⚠
nuclear movement protein
— OG7
C4B63_12g153 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_70g129 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_193g9 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
C4B63_25g216 ⚠
conserved hypothetical protein
— OG7
C4B63_25g215 ⚠
tRNA (cytosine(34)-C(5))-methyltransferase
— OG7
C4B63_4g245 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
C4B63_25g214 ⚠
conserved hypothetical protein
— OG7
C4B63_7g79 ⚠
aspartyl-tRNA synthetase
— OG7
C4B63_147g74 ⚠
conserved hypothetical protein
— Both
C4B63_9g266 ⚠
paraflagellar rod protein 5
— OG7
C4B63_10g289 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_9g267 ⚠
paraflagellar rod protein 5
— OG7
C4B63_10g290 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_10g288 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_10g287 ⚠
Paraflagellar rod protein 2
— OG7
C4B63_52g161 ⚠
tyrosyl-tRNA synthetase
— OG7
C4B63_124g1 ⚠
phosphatidylinositol 3-kinase
— OG7
C4B63_114g43 ⚠
conserved hypothetical protein
— Both
C4B63_40g126 ⚠
TOM1-like protein 9
— Both
C4B63_25g192 ⚠
NAA35
— Both
C4B63_58g143 ⚠
Lupus La protein homolog
— Both
C4B63_78g18 ⚠
conserved hypothetical protein
— Both
C4B63_425g4 ⚠
tyrosyl or methionyl-tRNA synthetase
— Both
C4B63_79g37 ⚠
methionyl-tRNA synthetase
— Both
C4B63_11g9 ⚠
eukaryotic translation initiation factor 3 su
— Both
C4B63_52g157 ⚠
serine hydroxymethyltransferase
— Both
C4B63_12g237 ⚠
eukaryotic release factor 3
— OG6
C4B63_2g430 ⚠
heat shock protein
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.