C4B63_2g447

Unc104-like kinesin(fragment)
Trypanosoma cruzi Dm28c 2018 OG6: OG6_136373 OG7: OG7_0000136 82 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 82 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_30g161 ⚠
glutamine synthetase
— OG6
C4B63_6g322 ⚠
conserved hypothetical protein
— OG6
C4B63_137g49 ⚠
conserved hypothetical protein
— OG6
C4B63_69g156 ⚠
conserved hypothetical protein
— OG6
C4B63_22g82 ⚠
conserved hypothetical protein
— OG6
C4B63_26g231 ⚠
ubiquitin hydrolase(fragment)
— OG6
C4B63_26g232 ⚠
ubiquitin hydrolase(fragment)
— OG6
C4B63_4g477 ⚠
Probable ATP-dependent RNA helicase DHX35
— OG6
C4B63_7g423 ⚠
proteasome beta 7 subunit
— OG6
C4B63_2g566 ⚠
phenylalanyl-tRNA synthetase
— OG6
C4B63_143g20 ⚠
glutamine synthetase
— OG6
C4B63_31g178 ⚠
Zinc phosphodiesterase ELAC protein 2
— OG6
C4B63_102g62 ⚠
conserved hypothetical protein
— OG6
C4B63_168g17 ⚠
conserved hypothetical protein
— OG6
C4B63_1g24 ⚠
conserved hypothetical protein
— OG6
C4B63_47g47 ⚠
U3 small nucleolar RNA-interacting protein 2
— OG6
C4B63_9g378 ⚠
conserved hypothetical protein
— OG6
C4B63_7g85 ⚠
pre-mRNA splicing factor ATP-dependent RNA he
— OG6
C4B63_101g26 ⚠
conserved hypothetical protein
— OG6
C4B63_7g142 ⚠
kinesin
— OG6
C4B63_2g18 ⚠
conserved hypothetical protein
— OG6
C4B63_293g23 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_18g156 ⚠
protein mkt1
— OG6
C4B63_267g91c ⚠
DNA-directed RNA polymerase I subunit RPB10
— OG6
C4B63_46g417c ⚠
DNA-directed RNA polymerase I subunit
— OG6
C4B63_12g1641c ⚠
DNA-directed RNA polymerase I subunit RPB10
— OG6
C4B63_18g20 ⚠
Protein will die slowly
— OG6
C4B63_34g222 ⚠
conserved hypothetical protein
— OG6
C4B63_34g220 ⚠
conserved hypothetical protein
— OG6
C4B63_34g221 ⚠
conserved hypothetical protein
— OG6
C4B63_49g160 ⚠
ATP-dependent DEAD/H RNA helicase
— OG6
C4B63_2g19 ⚠
conserved hypothetical protein
— OG6
C4B63_293g24 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g21 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_293g22 ⚠
ATP-dependent DEAD/H RNA helicase(fragment)
— OG6
C4B63_85g46 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG6
C4B63_26g275 ⚠
protein phosphatase 2A regulatory subunit
— OG6
C4B63_134g35 ⚠
ubiquitin hydrolase
— OG6
C4B63_35g128 ⚠
ubiquitin hydrolase
— OG6
C4B63_4g506 ⚠
Microtubule Associated kinase (CAP-Gly domain
— OG6
C4B63_31g177 ⚠
ribonuclease Z
— OG6
C4B63_295g26 ⚠
glutamate dehydrogenase
— OG6
C4B63_24g277 ⚠
conserved hypothetical protein
— OG6
C4B63_24g275 ⚠
conserved hypothetical protein
— OG6
C4B63_183g17 ⚠
conserved hypothetical protein
— OG6
C4B63_38g148 ⚠
DENN (AEX-3) domain containing protein
— OG6
C4B63_183g16 ⚠
conserved hypothetical protein
— OG6
C4B63_18g263 ⚠
SPA/DENN domain containing protein
— OG6
C4B63_18g295 ⚠
conserved hypothetical protein
— OG6
C4B63_138g26 ⚠
translation-associated element 2
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.