C4B63_31g115

eukaryotic translation initiation factor 2 beta subunit
Trypanosoma cruzi Dm28c 2018 OG6: OG6_101265 OG7: OG7_0006235 24 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Network view all shared interactors, plus up to 150 more
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Interactions 24 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_23g240
Eukaryotic translation initiation factor 2 su
— Both
C4B63_45g105 ⚠
DNA polymerase sigma
— OG7
C4B63_8g520 ⚠
DNA polymerase sigma-like protein
— OG7
C4B63_55g67 ⚠
DNA-directed rna polymerase I largest subunit
— OG7
C4B63_4g264 ⚠
Protein kintoun
— OG7
C4B63_4g265 ⚠
pre-RNA processing PIH1/Nop17
— OG7
C4B63_47g56 ⚠
RNA polymerase IIA largest subunit
— Both
C4B63_321g29 ⚠
RNA polymerase IIA largest subunit
— Both
C4B63_255g16 ⚠
RNA polymerase IIA largest subunit
— Both
C4B63_358g16 ⚠
RNA polymerase IIA largest subunit
— Both
C4B63_104g75 ⚠
RNA polymerase IIA largest subunit
— Both
C4B63_104g76 ⚠
RNA polymerase IIA largest subunit
— Both
C4B63_2g215 ⚠
PIH1 domain-containing protein 1
— Both
C4B63_45g210
pre-rrna-processing protein tsr1 homolog
— Both
C4B63_2g558
eukaryotic peptide chain release factor subun
— Both
C4B63_18g204
3-hydroxy-3-methylglutaryl-CoA reductase
— Both
C4B63_38g158 ⚠
Poly(A) RNA polymerase cid14
— Both
C4B63_97g18
heat shock protein 110
— OG6
C4B63_16g11 ⚠
5'-AMP-activated protein kinase subunit beta
— Both
C4B63_1g74 ⚠
eukaryotic translation initiation factor 2 su
— Both
C4B63_5g417 ⚠
eukaryotic translation initiation factor 2 su
— Both
C4B63_314g10 ⚠
5'-AMP-activated protein kinase subunit beta
— Both
C4B63_24g197
nucleolar protein
— Both
C4B63_14g200
conserved hypothetical protein
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.