LAEL147_000310500

tRNA (Uracil-5-)-methyltransferase, putative
Leishmania aethiopica L147 OG6: OG6_100839 OG7: OG7_0004255 96 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 96 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000831700 ⚠
NOL1/NOP2/sun family, putative
— Both
LAEL147_000254200 ⚠
NOL1/NOP2/sun family, putative
— OG7
LAEL147_000542400 ⚠
NOL1/NOP2/sun family, putative
— Both
LAEL147_000269100 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LAEL147_000425700
hypothetical protein, conserved
— Both
LAEL147_000484800 ⚠
rrp44p homologue, putative
— OG7
LAEL147_000283400 ⚠
ABC transport system ATP-binding protein, put
— Both
LAEL147_000045300 ⚠
inorganic pyrophosphatase, putative
— Both
LAEL147_000148100 ⚠
acidocalcisomal pyrophosphatase
— Both
LAEL147_000664000
Gar1/Naf1 RNA binding region containing prote
— Both
LAEL147_000351600
GDP-mannose pyrophosphorylase
— Both
LAEL147_000485900 ⚠
DIS3-like exonuclease, putative
— Both
LAEL147_000348700
alanyl-tRNA synthetase, putative
— Both
LAEL147_000401300 ⚠
cleavage and polyadenylation specificity fact
— Both
LAEL147_000870300
isoleucyl-tRNA synthetase, putative
— Both
LAEL147_000067600
hypothetical protein, conserved
— Both
LAEL147_000807600 ⚠
stress-inducible protein STI1 homolog
— OG6
LAEL147_000194900 ⚠
N-terminal conserved domain of Nudc./CS domai
— Both
LAEL147_000515000 ⚠
tryptophanyl-tRNA synthetase, putative
— Both
LAEL147_000507400 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LAEL147_000808500
PUB domain containing protein, putative
— Both
LAEL147_000206000 ⚠
tyrosyl-tRNA synthetase, putative
— Both
LAEL147_000245000 ⚠
Dihydrouridine synthase (Dus), putative
— Both
LAEL147_000205600 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LAEL147_000198800
hypothetical protein
— OG6
LAEL147_000479700 ⚠
TPR-repeat protein, putative
— OG6
LAEL147_000753500
hypothetical protein, conserved
— Both
LAEL147_000338800 ⚠
Putative tRNA binding domain containing prote
— OG7
LAEL147_000387500 ⚠
translation initiation factor IF-2, putative
— OG7
LAEL147_000312000 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000311900 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000780700 ⚠
pentatricopeptide repeat domain containing pr
— OG7
LAEL147_000536300 ⚠
hypothetical protein, conserved
— OG7
LAEL147_000681100 ⚠
protein kinase, putative
— OG7
LAEL147_000854200 ⚠
glycosyl hydrolase-like protein
— OG7
LAEL147_000322800 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LAEL147_000551200 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LAEL147_000875400 ⚠
rab-like GTPase activating protein, putative
— OG7
LAEL147_000049200 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LAEL147_000715800 ⚠
Dihydrouridine synthase (Dus), putative
— OG7
LAEL147_000553700 ⚠
nuclear movement protein, putative
— OG7
LAEL147_000235500 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— OG7
LAEL147_000606500 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LAEL147_000354300 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LAEL147_000812300 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LAEL147_000668100 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LAEL147_000037400 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LAEL147_000228500 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LAEL147_000737800 ⚠
cleavage and polyadenylation specificity fact
— OG7
LAEL147_000760000
protein kinase, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.