LAMA_000137800

Histone deacetylase domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_100220 OG7: OG7_0001154 68 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 68 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000450700 ⚠
DEAD/DEAH box helicase/Helicase conserved C-t
— OG7
LAMA_000820400 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LAMA_000278200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000090400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000253000 ⚠
WW domain containing protein, putative
— OG7
LAMA_000319700 ⚠
AAA domain/Adenylate kinase, putative
— OG7
LAMA_000279000 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LAMA_000595400 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LAMA_000667700 ⚠
hypothetical protein
— OG7
LAMA_000684300 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000127300 ⚠
RNA polymerase Rpb3/Rpb11 dimerisation domain
— OG7
LAMA_000138300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000360300 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000715600 ⚠
N-terminal domain of ribose phosphate pyropho
— OG7
LAMA_000133900 ⚠
N-terminal domain of ribose phosphate pyropho
— Both
LAMA_000128800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— Both
LAMA_000029700 ⚠
hypothetical protein, conserved
— Both
LAMA_000514200 ⚠
hypothetical protein, conserved
— OG7
LAMA_000698500 ⚠
ABC transporter, putative
— OG7
LAMA_000297600 ⚠
ABC transporter, putative
— OG7
LAMA_000801800 ⚠
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG7
LAMA_000411400 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000065800 ⚠
RecF/RecN/SMC N terminal domain/AAA domain/SM
— OG7
LAMA_000338000 ⚠
Tubulin binding cofactor C, putative
— OG7
LAMA_000059100 ⚠
Adenylate kinase/AAA domain containing protei
— OG7
LAMA_000221900 ⚠
FYVE zinc finger/Ras family, putative
— OG7
LAMA_000029800 ⚠
hypothetical protein, conserved
— Both
LAMA_000241600 ⚠
Holliday junction DNA helicase RuvB P-loop do
— OG7
LAMA_000542000 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000790700 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LAMA_000801700 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000298800 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000809200 ⚠
FYVE zinc finger containing protein, putative
— OG7
LAMA_000668200 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG7
LAMA_000515800 ⚠
MORN repeat/FYVE zinc finger containing prote
— Both
LAMA_000757500 ⚠
hypothetical protein, conserved
— Both
LAMA_000764500 ⚠
GRIP domain containing protein, putative
— Both
LAMA_000599000 ⚠
hypothetical protein, conserved
— Both
LAMA_000751700 ⚠
RNA-binding signal recognition particle 68, p
— Both
LAMA_000329200 ⚠
Gamma tubulin complex component N-terminal, p
— Both
LAMA_000346500 ⚠
hypothetical protein, conserved
— Both
LAMA_000652000 ⚠
Biotin carboxylase, N-terminal domain/Carbamo
— Both
LAMA_000162200 ⚠
Chromatin assembly factor 1 subunit A, putati
— Both
LAMA_000706700 ⚠
hypothetical protein, conserved
— Both
LAMA_000203300 ⚠
hypothetical protein, conserved
— Both
LAMA_000084000 ⚠
hypothetical protein, conserved
— Both
LAMA_000185800 ⚠
Ubiquitin carboxyl-terminal hydrolase, putati
— Both
LAMA_000597100 ⚠
WW domain containing protein, putative
— Both
LAMA_000480300 ⚠
hypothetical protein, conserved
— Both
LAMA_000410500 ⚠
Adenylate kinase/AAA domain containing protei
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.