LAMA_000385000

Cyclic nucleotide-binding domain/PAS domain/PAS fold/Protein tyrosine kinase/Protein kinase domain containing protein, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_147529 OG7: OG7_0000432 43 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 43 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000071100 ⚠
CPSF A subunit region containing protein, put
— OG6
LAMA_000435500
Beige/BEACH domain containing protein, putati
— OG6
LAMA_000109600
hypothetical protein, conserved
— OG6
LAMA_000335600
Phosphatidylinositol 3- and 4-kinase, putativ
— OG6
LAMA_000681500
SpoU rRNA Methylase family, putative
— OG6
LAMA_000742200
hypothetical protein, conserved
— OG6
LAMA_000051500
KH domain containing protein, putative
— OG6
LAMA_000045400 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG6
LAMA_000045300 ⚠
hypothetical protein
— OG6
LAMA_000281500
WD domain, G-beta repeat/Dip2/Utp12 Family, p
— OG6
LAMA_000164400
hypothetical protein, conserved
— OG6
LAMA_000635500
Protein phosphatase 2C, putative
— OG6
LAMA_000071000 ⚠
Mono-functional DNA-alkylating methyl methane
— OG6
LAMA_000255000
RNA polymerase Rpb1, domain 2/RNA polymerase
— OG6
LAMA_000267800 ⚠
N-terminal helicase PWI domain/DEAD/DEAH box
— OG6
LAMA_000197500 ⚠
DEAD/DEAH box helicase/Type III restriction e
— OG6
LAMA_000128800
AAA ATPase domain/RecF/RecN/SMC N terminal do
— OG6
LAMA_000281400
hypothetical protein, conserved
— OG6
LAMA_000215700
WD domain, G-beta repeat, putative
— OG6
LAMA_000232600
hypothetical protein, conserved
— OG6
LAMA_000200700
hypothetical protein, conserved
— OG6
LAMA_000133900
N-terminal domain of ribose phosphate pyropho
— OG6
LAMA_000481000
hypothetical protein, conserved
— OG6
LAMA_000609800
hypothetical protein, conserved
— OG6
LAMA_000019300
Cullin family, putative
— OG6
LAMA_000410500
Adenylate kinase/AAA domain containing protei
— OG6
LAMA_000536900
Right handed beta helix region/Periplasmic co
— OG6
LAMA_000746000
Glycosyl hydrolase family 65 central catalyti
— OG6
LAMA_000661400
Pan3 Pseudokinase domain containing protein,
— OG6
LAMA_000515800
MORN repeat/FYVE zinc finger containing prote
— OG6
LAMA_000652000
Biotin carboxylase, N-terminal domain/Carbamo
— OG6
LAMA_000484600
RNA polymerase beta subunit/RNA polymerase Rp
— OG6
LAMA_000358900
Adaptin N terminal region/non-SMC mitotic con
— OG6
LAMA_000358700
Glycosyl hydrolase family 65, N-terminal doma
— OG6
LAMA_000751700
RNA-binding signal recognition particle 68, p
— OG6
LAMA_000588300
Ubiquitin carboxyl-terminal hydrolase/Exonucl
— OG6
LAMA_000622600
CPSF A subunit region containing protein, put
— OG6
LAMA_000634500
Protein of unknown function (DUF3638)/Protein
— OG6
LAMA_000706700
hypothetical protein, conserved
— OG6
LAMA_000440400
hypothetical protein, conserved
— OG6
LAMA_000569900
Holliday junction DNA helicase RuvB P-loop do
— OG6
LAMA_000512400
hypothetical protein, conserved
— OG6
LAMA_000791400
hypothetical protein, conserved
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.