LINF_300031100

formate--tetrahydrofolate ligase
Leishmania infantum JPCM5 OG6: OG6_100216 OG7: OG7_0002740 193 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 193 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LINF_350015200 ⚠
protein kinase - putative
— OG6
LINF_300011700 ⚠
Phosphoinositide-specific phospholipase C - e
— OG6
LINF_310036800 ⚠
KH domain/Domain of unknown function (DUF1771
— OG6
LINF_320022600 ⚠
protein phosphatase 2C - putative
— OG6
LINF_250027000 ⚠
2 -4-dihydroxyhept-2-ene-1 -7-dioic acid aldo
— OG6
LINF_360031600 ⚠
dipeptidyl-peptidase 8-like serine peptidase
— Both
LINF_320033200 ⚠
superoxide dismutase - putative
— OG6
LINF_300006800 ⚠
2-hydroxy-3-oxopropionate reductase - putativ
— OG6
LINF_320014700 ⚠
Alpha/beta hydrolase family - putative
— OG6
LINF_320016700 ⚠
exportin 1 - putative
— OG6
LINF_360005700 ⚠
stress-inducible protein STI1 homolog
— OG6
LINF_200011400 ⚠
hypothetical protein - conserved
— OG6
LINF_230006100 ⚠
GDP-mannose pyrophosphorylase
— Both
LINF_290005500 ⚠
tryptophanyl-tRNA synthetase - putative
— Both
LINF_260024400 ⚠
deoxyhypusine hydroxylase - putative
— OG6
LINF_180011700 ⚠
serine/threonine kinase-like protein - putati
— OG6
LINF_310016800 ⚠
biotin/lipoate protein ligase-like protein
— OG6
LINF_270013300 ⚠
UBA/TS-N domain containing protein - putative
— OG6
LINF_140019600 ⚠
serine hydroxymethyltransferase (SHMT-L)
— Both
LINF_320024000 ⚠
iron superoxide dismutase - putative
— OG6
LINF_250006800 ⚠
cleavage and polyadenylation specificity fact
— Both
LINF_340045400 ⚠
phosphomannomutase-like protein
— OG6
LINF_250028200 ⚠
Translation initiation factor eIF3 subunit -
— Both
LINF_200021600 ⚠
tRNA (Uracil-5-)-methyltransferase/Protein-L-
— Both
LINF_360024300 ⚠
5'-3' exoribonuclease D - putative
— OG6
LINF_270018900 ⚠
WD domain - G-beta repeat - putative
— OG6
LINF_120005100 ⚠
PITH domain-containing protein
— OG6
LINF_070015200 ⚠
serine/threonine kinase - putative
— OG6
LINF_160011100 ⚠
dihydroorotase - putative
— OG6
LINF_260032900 ⚠
6-phosphogluconolactonase
— OG6
LINF_110007000 ⚠
acidocalcisomal pyrophosphatase
— Both
LINF_360011200 ⚠
Elongation factor G1 - mitochondrial - putati
— OG6
LINF_180005900 ⚠
alpha glucosidase II subunit - putative
— Both
LINF_350047400 ⚠
Protein of unknown function (DUF2009) - putat
— OG6
LINF_290019000 ⚠
carnitine/choline acetyltransferase - putativ
— OG6
LINF_300031200 ⚠
RNA-binding protein - putative
— OG6
LINF_340045100 ⚠
hypothetical protein - conserved
— Both
LINF_340028800 ⚠
asparaginyl-tRNA synthetase - putative
— Both
LINF_270030600 ⚠
protein phosphatase-like protein
— OG6
LINF_350005200 ⚠
pyruvate kinase
— OG6
LINF_260029200 ⚠
Zn-finger in Ran binding protein and others/S
— OG6
LINF_170009800 ⚠
Dihydrouridine synthase (Dus) - putative
— Both
LINF_180007900 ⚠
Dephospho-CoA kinase - putative
— OG6
LINF_280019500 ⚠
haloacid dehalogenase-like hydrolase - putati
— OG6
LINF_180014100 ⚠
cyclosporin 16 - putative
— OG6
LINF_300038700 ⚠
UV excision repair RAD23-like protein
— Both
LINF_360078100 ⚠
hypothetical protein - conserved
— OG6
LINF_330005900 ⚠
hypothetical protein - conserved
— OG6
LINF_350005300 ⚠
pyruvate kinase
— OG6
LINF_360050100 ⚠
glycosyl hydrolase-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.