TcIL3000_10_9220

DNA mismatch repair protein MSH2, putative
Trypanosoma congolense IL3000 OG6: OG6_102031 OG7: OG7_0001336 69 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 69 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcIL3000_10_710 ⚠
hook complex protein, conserved (fragment)
— OG7
TcIL3000_9_5080 ⚠
replication factor C, subunit 3, putative (fr
— OG7
TcIL3000_0_50610 ⚠
Replication Factor C Subunit 1-related protei
— OG7
TcIL3000_10_6860 ⚠
replication factor C subunit 3, putative
— OG7
TcIL3000_0_25410 ⚠
ATPase family associated with various cellula
— OG7
TcIL3000_0_39040 ⚠
hypothetical protein (fragment)
— OG7
TcIL3000.11.10020 ⚠
replication factor C, subunit 4, putative
— OG7
TcIL3000_0_32630 ⚠
hypothetical protein
— OG7
TcIL3000_0_34520 ⚠
hypothetical protein, conserved
— OG7
TcIL3000_10_7230 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_9_5450 ⚠
IQ calmodulin-binding motif containing protei
— OG7
TcIL3000_0_29030 ⚠
geranylgeranyl transferase type II beta subun
— OG7
TcIL3000_4_310 ⚠
geranylgeranyl transferase type II beta subun
— OG7
TcIL3000_9_1740 ⚠
mismatch repair protein MSH3, putative
— Both
TcIL3000.11.6930 ⚠
leucine-rich repeat protein (LRRP), putative
— Both
TcIL3000_0_13010 ⚠
WD domain, G-beta repeat, putative
— Both
TcIL3000_0_21000 ⚠
hypothetical protein, conserved (fragment)
— Both
TcIL3000_0_30110 ⚠
WD domain, G-beta repeat, putative
— Both
TcIL3000_0_31300 ⚠
co-chaperone GrpE, putative
— OG7
TcIL3000.11.4540 ⚠
serine/threonine protein kinase, putative
— OG7
TcIL3000_0_55150 ⚠
ubiquitin-protein ligase, putative (fragment)
— OG7
TcIL3000_9_5670 ⚠
ubiquitin-protein ligase, putative (fragment)
— OG7
TcIL3000_10_8600 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_9_1520 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
TcIL3000_3_880 ⚠
U6 snRNA-associated Sm-like protein LSm8p
— OG7
TcIL3000_9_1040 ⚠
U6 snRNA-associated Sm-like protein LSm6p, Sm
— OG7
TcIL3000_0_48480 ⚠
hypothetical protein, conserved
— OG7
TcIL3000.11.6900 ⚠
PUB domain containing protein, putative
— Both
TcIL3000_6_2060 ⚠
hypothetical protein, conserved (fragment)
— OG7
TcIL3000_8_1450 ⚠
ubiquitin-protein ligase, putative
— OG7
TcIL3000_0_25450 ⚠
SPRY domain containing protein, putative (fra
— OG7
TcIL3000_0_11960 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
TcIL3000_0_55120 ⚠
hypothetical protein
— OG7
TcIL3000_8_5130 ⚠
WW domain containing protein, putative
— OG7
TcIL3000_10_7240 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
TcIL3000_9_3550 ⚠
hypothetical protein, conserved
— Both
TcIL3000_10_10630 ⚠
hypothetical protein, conserved
— Both
TcIL3000_10_1270 ⚠
protein kinase, putative (fragment)
— Both
TcIL3000_0_08730 ⚠
hypothetical protein, conserved
— Both
TcIL3000_0_09130 ⚠
ATP-dependent RNA helicase, putative
— OG6
TcIL3000_0_45240 ⚠
ATP-dependent RNA helicase, putative
— OG6
TcIL3000_7_170 ⚠
protein farnesyltransferase beta subunit (fra
— Both
TcIL3000_5_3890 ⚠
ubiquitin-activating enzyme E1, putative
— Both
TcIL3000_4_1570 ⚠
hypothetical protein, conserved
— Both
TcIL3000_0_60340 ⚠
hypothetical protein, conserved (fragment)
— Both
TcIL3000_9_990 ⚠
endo-beta-N-acetylglucosaminidase, putative
— Both
TcIL3000.11.2830 ⚠
ribosome assembly protein RRB1, putative
— Both
TcIL3000_9_5150 ⚠
RNA-binding protein, putative (fragment)
— Both
TcIL3000.11.11720 ⚠
Calponin homology (CH) domain containing prot
— Both
TcIL3000_10_1090 ⚠
Domain of unknown function (DUF4042), putativ
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.