C4B63_20g178

dihydrolipoyl dehydrogenase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100523 OG7: OG7_0001637 36 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Network view all shared interactors, plus up to 150 more
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Interactions 36 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_6g148 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_179g1 ⚠
2-oxoglutarate dehydrogenase E1 component(fra
— Both
C4B63_19g275 ⚠
2-oxoglutarate dehydrogenase subunit
— Both
C4B63_11g281 ⚠
Mucin-associated surface protein (MASP)
— OG6
C4B63_40g18 ⚠
2-oxoglutarate dehydrogenase E1 component
— Both
C4B63_253g15 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_54g69 ⚠
aspartate aminotransferase
— Both
C4B63_6g146 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_28g64 ⚠
aspartate aminotransferase
— Both
C4B63_32g52
Succinate dehydrogenase [ubiquinone] flavopro
— Both
C4B63_10g148 ⚠
carnitine/choline acetyltransferase
— OG6
C4B63_10g147 ⚠
carnitine O-acetyltransferase(fragment)
— OG6
C4B63_7g361
phosphomannomutase-like protein
— Both
C4B63_42g217
protein phosphatase
— OG6
C4B63_30g261 ⚠
deoxyribose-phosphate aldolase
— Both
C4B63_163g21 ⚠
deoxyribose-phosphate aldolase
— Both
C4B63_112g33 ⚠
haloacid dehalogenase hydrolase
— OG7
C4B63_30g112 ⚠
haloacid dehalogenase hydrolase
— OG7
C4B63_227g20 ⚠
pyruvate kinase 2
— Both
C4B63_57g98
succinyl-CoA ligase
— Both
C4B63_26g282 ⚠
arginine kinase
— Both
C4B63_6g219
hd phosphohydrolase family protein
— Both
C4B63_26g286 ⚠
arginine kinase
— Both
C4B63_21g253
Mitogen-activated protein kinase 10
— OG6
C4B63_40g46
ATP-dependent protease subunit HslV
— Both
C4B63_4g137 ⚠
N-myristoyl transferase
— Both
C4B63_4g146 ⚠
pyruvate kinase 2
— Both
C4B63_14g188
UPF0769 protein C21orf59 homolog B
— Both
C4B63_7g133
pyroglutamyl-peptidase I
— Both
C4B63_26g278 ⚠
arginine kinase
— Both
C4B63_11g8
succinyl-CoA synthetase alpha subunit
— Both
C4B63_4g136 ⚠
N-myristoyl transferase
— Both
C4B63_238g18 ⚠
GMP synthase(fragment)
— Both
C4B63_142g6 ⚠
GMP synthase
— Both
C4B63_35g125
transaldolase
— Both
C4B63_179g2 ⚠
2-oxoglutarate dehydrogenase subunit
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.