C4B63_57g98

succinyl-CoA ligase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100409 OG7: OG7_0003652 65 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 65 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_11g8
succinyl-CoA synthetase alpha subunit
— +2 more Both
C4B63_6g146 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_32g217 ⚠
2-amino-3-ketobutyrate coenzyme A ligase
— Both
C4B63_32g214 ⚠
2-amino-3-ketobutyrate coenzyme A ligase
— Both
C4B63_7g361
phosphomannomutase-like protein
— Both
C4B63_10g147 ⚠
carnitine O-acetyltransferase(fragment)
— OG6
C4B63_10g148 ⚠
carnitine/choline acetyltransferase
— OG6
C4B63_6g148 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_28g64 ⚠
aspartate aminotransferase
— Both
C4B63_36g68 ⚠
mucin TcMUCII
— OG6
C4B63_54g69 ⚠
aspartate aminotransferase
— Both
C4B63_253g15 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_20g213 ⚠
enoyl-CoA hydratase/isomerase family protein
— Both
C4B63_76g16 ⚠
NADH-cytochrome b5 reductase
— Both
C4B63_83g35 ⚠
NADH-cytochrome b5 reductase
— Both
C4B63_20g361
uracil phosphoribosyltransferase
— Both
C4B63_32g225
3-hydroxy-3-methylglutaryl-CoA synthase
— Both
C4B63_42g217
protein phosphatase
— OG6
C4B63_282g12 ⚠
ribose 5-phosphate isomerase type B
— Both
C4B63_30g261 ⚠
deoxyribose-phosphate aldolase
— Both
C4B63_163g21 ⚠
deoxyribose-phosphate aldolase
— Both
C4B63_4g486 ⚠
glycosomal malate dehydrogenase
— OG7
C4B63_47g33 ⚠
malate dehydrogenase
— OG7
C4B63_22g311 ⚠
3-phosphoglycerate kinase, glycosomal
— OG7
C4B63_54g18 ⚠
serine palmitoyltransferase
— OG7
C4B63_7g356 ⚠
serine-palmitoyl-CoA transferase
— OG7
C4B63_112g33 ⚠
haloacid dehalogenase hydrolase
— OG7
C4B63_30g112 ⚠
haloacid dehalogenase hydrolase
— OG7
C4B63_9g494 ⚠
cytochrome-b5 reductase
— OG7
C4B63_46g107 ⚠
NADH-cytochrome b5 reductase
— OG7
C4B63_87g24 ⚠
nonspecific lipid-transfer protein
— OG7
C4B63_70g87 ⚠
NADH-cytochrome b5 reductase
— OG7
C4B63_19g260 ⚠
reductase
— OG7
C4B63_238g18 ⚠
GMP synthase(fragment)
— Both
C4B63_56g86
methylthioadenosine phosphorylase
— Both
C4B63_26g282 ⚠
arginine kinase
— Both
C4B63_20g178
dihydrolipoyl dehydrogenase
— Both
C4B63_6g219
hd phosphohydrolase family protein
— Both
C4B63_26g286 ⚠
arginine kinase
— Both
C4B63_21g253
Mitogen-activated protein kinase 10
— OG6
C4B63_22g312 ⚠
phosphoglycerate kinase
— Both
C4B63_40g46
ATP-dependent protease subunit HslV
— Both
C4B63_4g137 ⚠
N-myristoyl transferase
— Both
C4B63_4g146 ⚠
pyruvate kinase 2
— Both
C4B63_227g20 ⚠
pyruvate kinase 2
— Both
C4B63_7g133
pyroglutamyl-peptidase I
— Both
C4B63_26g278 ⚠
arginine kinase
— Both
C4B63_18g148 ⚠
PAS-domain containing phosphoglycerate kinase
— Both
C4B63_4g136 ⚠
N-myristoyl transferase
— Both
C4B63_20g212 ⚠
enoyl-CoA hydratase/isomerase family protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.