C4B63_26g286

arginine kinase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_100675 OG7: OG7_0003573 48 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 48 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_7g361 ⚠
phosphomannomutase-like protein
— Both
C4B63_4g69 ⚠
mitogen-activated protein kinase kinase kinas
— OG6
C4B63_35g125 ⚠
transaldolase
— Both
C4B63_23g212 ⚠
serine/threonine-protein kinase
— OG6
C4B63_23g211 ⚠
protein kinase(fragment)
— OG6
C4B63_54g69 ⚠
aspartate aminotransferase
— Both
C4B63_253g15 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_6g146 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_28g64 ⚠
aspartate aminotransferase
— Both
C4B63_6g148 ⚠
haloacid dehalogenase-like hydrolase
— Both
C4B63_10g148 ⚠
carnitine/choline acetyltransferase
— OG6
C4B63_10g147 ⚠
carnitine O-acetyltransferase(fragment)
— OG6
C4B63_142g6 ⚠
GMP synthase
— Both
C4B63_42g217 ⚠
protein phosphatase
— OG6
C4B63_30g145 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
C4B63_11g8 ⚠
succinyl-CoA synthetase alpha subunit
— Both
C4B63_4g137 ⚠
N-myristoyl transferase
— Both
C4B63_4g136 ⚠
N-myristoyl transferase
— Both
C4B63_30g261 ⚠
deoxyribose-phosphate aldolase
— Both
C4B63_163g21 ⚠
deoxyribose-phosphate aldolase
— Both
C4B63_26g289 ⚠
myo-inositol-1 phosphatase
— OG7
C4B63_22g311 ⚠
3-phosphoglycerate kinase, glycosomal
— OG7
C4B63_112g33 ⚠
haloacid dehalogenase hydrolase
— OG7
C4B63_30g112 ⚠
haloacid dehalogenase hydrolase
— OG7
C4B63_77g79 ⚠
aldose 1-epimerase-like protein
— Both
C4B63_21g253 ⚠
Mitogen-activated protein kinase 10
— OG6
C4B63_22g312 ⚠
phosphoglycerate kinase
— Both
C4B63_19g80 ⚠
epsin
— Both
C4B63_40g46 ⚠
ATP-dependent protease subunit HslV
— Both
C4B63_7g133 ⚠
pyroglutamyl-peptidase I
— Both
C4B63_19g77 ⚠
Secretory carrier-associated membrane protein
— Both
C4B63_18g148 ⚠
PAS-domain containing phosphoglycerate kinase
— Both
C4B63_25g252 ⚠
myo-inositol-1(or 4)-monophosphatase 1
— Both
C4B63_145g31 ⚠
aldose 1-epimerase-like protein
— Both
C4B63_314g15 ⚠
aldose 1-epimerase-like protein
— Both
C4B63_16g3 ⚠
aldose 1-epimerase-like protein
— Both
C4B63_6g219 ⚠
hd phosphohydrolase family protein
— Both
C4B63_16g4 ⚠
aldose 1-epimerase-like protein
— Both
C4B63_14g188 ⚠
UPF0769 protein C21orf59 homolog B
— Both
C4B63_19g141 ⚠
electron transfer flavoprotein
— Both
C4B63_57g98 ⚠
succinyl-CoA ligase
— Both
C4B63_354g1 ⚠
electron transfer flavoprotein
— Both
C4B63_4g146 ⚠
pyruvate kinase 2
— Both
C4B63_227g20 ⚠
pyruvate kinase 2
— Both
C4B63_20g178 ⚠
dihydrolipoyl dehydrogenase
— Both
C4B63_2g294 ⚠
40 kDa cyclophilin
— OG6
C4B63_7g72 ⚠
conserved hypothetical protein
— Both
C4B63_238g18 ⚠
GMP synthase(fragment)
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.