C4B63_42g77

heat shock protein
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146755 OG7: OG7_0000420 75 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 75 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_60g175
conserved hypothetical protein
— Both
C4B63_48g107 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_128g70 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_2g163 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_24g187
conserved hypothetical protein
— Both
C4B63_120g42 ⚠
Pseudouridylate synthase 7 homolog
— Both
C4B63_12g257 ⚠
Pseudouridylate synthase 7 homolog
— Both
C4B63_40g27
conserved hypothetical protein
— Both
C4B63_2g444
RRP12
— Both
C4B63_8g543
small GTP-binding protein
— Both
C4B63_48g110 ⚠
ATP-dependent DEAD/H RNA helicase
— OG7
C4B63_16g110
conserved hypothetical protein
— Both
C4B63_49g55 ⚠
conserved hypothetical protein
— Both
C4B63_293g3 ⚠
conserved hypothetical protein
— Both
C4B63_140g33 ⚠
conserved hypothetical protein
— Both
C4B63_129g45 ⚠
conserved hypothetical protein
— Both
C4B63_44g107 ⚠
conserved hypothetical protein
— Both
C4B63_10g111
conserved hypothetical protein
— Both
C4B63_51g197 ⚠
conserved hypothetical protein
— Both
C4B63_30g181 ⚠
rRNA methyltransferase 1, mitochondrial
— OG7
C4B63_15g5 ⚠
zinc-finger CCCH domain containing protein 11
— OG7
C4B63_12g2035c ⚠
zinc-finger protein 2
— OG7
C4B63_397g11 ⚠
zinc-finger CCCH domain containing protein 11
— OG7
C4B63_2g431 ⚠
GTPase protein
— OG7
C4B63_128g61 ⚠
50S ribosome-binding GTPase
— OG7
C4B63_128g62 ⚠
50S ribosome-binding GTPase
— OG7
C4B63_56g32 ⚠
GTPase
— OG7
C4B63_83g24 ⚠
zinc-finger (CCCH type) protein
— OG7
C4B63_128g63 ⚠
GTP-binding protein
— OG7
C4B63_51g196 ⚠
conserved hypothetical protein
— Both
C4B63_91g35 ⚠
GTPase
— OG7
C4B63_8g202 ⚠
GTP-binding protein
— OG7
C4B63_9g446 ⚠
Probable methyltransferase TARBP1
— OG7
C4B63_7g129 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_83g25 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_469g4 ⚠
ATP-dependent RNA helicase(fragment)
— OG7
C4B63_9g518 ⚠
ATP-dependent RNA helicase
— OG7
C4B63_469g3 ⚠
ATP-dependent RNA helicase(fragment)
— OG7
C4B63_11g71
conserved hypothetical protein
— Both
C4B63_84g79
conserved hypothetical protein
— Both
C4B63_69g21
pseudouridylate synthase-like protein
— Both
C4B63_57g103
conserved hypothetical protein
— Both
C4B63_442g1 ⚠
ATP-dependent DEAD/H RNA helicase
— Both
C4B63_43g147
mitochondrial RNA binding complex 1 subunit
— Both
C4B63_72g88 ⚠
conserved hypothetical protein
— Both
C4B63_4g456 ⚠
conserved hypothetical protein
— Both
C4B63_340g8 ⚠
conserved hypothetical protein
— Both
C4B63_31g78
conserved hypothetical protein
— Both
C4B63_2g691 ⚠
30S Ribosomal protein S17
— Both
C4B63_19g35
conserved hypothetical protein
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.