LAEL147_000029200

Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger) containing protein, putative
Leishmania aethiopica L147 OG6: OG6_144850 OG7: OG7_0049023 101 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 101 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAEL147_000340500
guide RNA associated protein, GAP2, putative
— Both
LAEL147_000767100
casein kinase II, putative
— OG6
LAEL147_000863000
Calponin homology (CH) domain containing prot
— Both
LAEL147_000609400
ARM-like helical domain-containing protein
— Both
LAEL147_000556500 ⚠
ubiquitin-protein ligase, putative
— Both
LAEL147_000565000
hypothetical protein, conserved
— Both
LAEL147_000354500
hypothetical protein, conserved
— Both
LAEL147_000040100 ⚠
TLD domain protein, conserved
— Both
LAEL147_000552200
hypothetical protein, conserved
— Both
LAEL147_000783400
RNA-binding protein, putative
— Both
LAEL147_000270400 ⚠
Prolyl-tRNA synthetase, C-terminal, putative
— Both
LAEL147_000383700 ⚠
replication factor C, subunit 1, putative
— Both
LAEL147_000686600
Ribosome assembly protein rrb1, putative
— Both
LAEL147_000334900 ⚠
transcription factor-like protein
— Both
LAEL147_000601900
Leucine-rich repeat - CC (cysteine-containing
— Both
LAEL147_000322200
HEAT-like repeat, putative
— Both
LAEL147_000632300
hypothetical protein, conserved
— Both
LAEL147_000268400
5-oxoprolinase, putative
— Both
LAEL147_000426000 ⚠
Lsm7p protein, putative
— Both
LAEL147_000034700
Nop14-like family, putative
— Both
LAEL147_000725600 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LAEL147_000758600
hypothetical protein, conserved
— Both
LAEL147_000588900 ⚠
ATP-dependent RNA helicase, putative
— OG6
LAEL147_000540600
aspartyl aminopeptidase, putative
— Both
LAEL147_000690900
glycosyl hydrolase-like protein
— Both
LAEL147_000502300
p21-C-terminal region-binding protein, putati
— Both
LAEL147_000250300 ⚠
guanosine monophosphate reductase
— OG6
LAEL147_000271200
hypothetical protein, conserved
— Both
LAEL147_000594900 ⚠
ras-like small GTPases, putative
— OG6
LAEL147_000589300 ⚠
CRAL/TRIO domain containing protein, putative
— Both
LAEL147_000152900 ⚠
aminopeptidase, putative
— Both
LAEL147_000042900 ⚠
DEAD/DEAH box helicase, putative
— Both
LAEL147_000031000
Soluble NSF attachment protein, SNAP, putativ
— Both
LAEL147_000632800 ⚠
HECT-domain (ubiquitin-transferase), putative
— Both
LAEL147_000438500
hypothetical protein, conserved
— Both
LAEL147_000155800
Leucine Rich repeat, putative
— Both
LAEL147_000264000 ⚠
Zn-finger in Ran binding protein and others/F
— Both
LAEL147_000778500
hypothetical protein, conserved
— Both
LAEL147_000270500 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LAEL147_000015500 ⚠
ras-like small GTPases, putative
— OG6
LAEL147_000730400
hypothetical protein, conserved
— Both
LAEL147_000285100
hypothetical protein, conserved
— Both
LAEL147_000800400
BRCA1 C Terminus (BRCT) domain containing pro
— Both
LAEL147_000270300 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LAEL147_000533600 ⚠
MORN repeat, putative
— Both
LAEL147_000440600 ⚠
farnesyltransferase beta subunit
— Both
LAEL147_000668700
DNA mismatch repair protein MSH2, putative
— Both
LAEL147_000291400 ⚠
inosine-5'-monophosphate dehydrogenase
— Both
LAEL147_000093300
hypothetical protein, conserved
— Both
LAEL147_000156100
PUB domain containing protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.