LAEL147_000320500

methionyl-tRNA synthetase

Leishmania aethiopica L147 OG6: OG6_101119 OG7: OG7_0003306 128 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 128 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LAEL147_000552900 histidyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003126 ↔ TCSYLVIO_007991 OG6 Tb927.10.1500 ↔ Tb927.6.2060 OG7 TCSYLVIO_003126 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.6.2060	Both
LAEL147_000183200 leucyl-tRNA synthetase, putative	—	OG6 Tb927.10.1500 ↔ Tb927.11.3730 OG6 TCSYLVIO_003028 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.11.3730 OG7 TCSYLVIO_003028 ↔ TCSYLVIO_007991	Both
LAEL147_000206000 ⚠ tyrosyl-tRNA synthetase, putative	—	OG6 Tb927.10.1500 ↔ Tb927.7.3620 OG6 TCSYLVIO_007991 ↔ TCSYLVIO_010624 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.7.3620 +2 more	Both
LAEL147_000235500 ⚠ tyrosyl or methionyl-tRNA synthetase-like pro	—	OG6 Tb927.10.1500 ↔ Tb927.7.2400 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.7.3620 +2 more	Both
LAEL147_000579900 valyl-tRNA synthetase, putative	—	OG6 Tb927.10.1500 ↔ Tb927.6.4480 OG6 TCSYLVIO_003345 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.6.4480 OG7 TCSYLVIO_003345 ↔ TCSYLVIO_007991	Both
LAEL147_000338800 ⚠ Putative tRNA binding domain containing prote	—	OG6 Tb927.10.1500 ↔ Tb927.7.2400 OG6 TCSYLVIO_001244 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001244 ↔ TCSYLVIO_007991 OG7 Tb927.10.1500 ↔ Tb927.7.3620 +2 more	Both
LAEL147_000153000 ⚠ aminopeptidase, putative	—	OG7 TCSYLVIO_005560 ↔ TCSYLVIO_007991	OG7
LAEL147_000753300 Thioredoxin, putative	—	OG6 TCSYLVIO_005083 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_005083 ↔ TCSYLVIO_007991	Both
LAEL147_000694000 ⚠ aminopeptidase, putative	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_007991	Both
LAEL147_000583300 ⚠ DNA ligase I, putative	—	OG6 TCSYLVIO_003375 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003375 ↔ TCSYLVIO_007991	Both
LAEL147_000305200 Pre-mRNA-splicing factor 38, putative	—	OG6 TCSYLVIO_007337 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_007337 ↔ TCSYLVIO_007991	Both
LAEL147_000581700 UV excision repair RAD23-like protein	—	OG6 TCSYLVIO_003361 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003361 ↔ TCSYLVIO_007991	Both
LAEL147_000258200 ⚠ kinetoplast polyadenylation/uridylation facto	—	OG6 TCSYLVIO_000834 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_000834 ↔ TCSYLVIO_007991	Both
LAEL147_000422300 hypothetical protein, conserved	—	OG6 TCSYLVIO_006404 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_006404 ↔ TCSYLVIO_007991	Both
LAEL147_000259100 ⚠ alpha glucosidase II subunit, putative	—	OG6 TCSYLVIO_006140 ↔ TCSYLVIO_007991 OG6 TCSYLVIO_006141 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_006140 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_006141 ↔ TCSYLVIO_007991	Both
LAEL147_000346000 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007991	Both
LAEL147_000345100 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007991	Both
LAEL147_000753500 hypothetical protein, conserved	—	OG6 TCSYLVIO_005084 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_005084 ↔ TCSYLVIO_007991	Both
LAEL147_000537900 UDP-glucose:Glycoprotein Glucosyltransferase,	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_007991	Both
LAEL147_000831700 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007991	Both
LAEL147_000542400 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007991	Both
LAEL147_000807600 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007991	OG6
LAEL147_000479700 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007991	OG6
LAEL147_000067600 hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007991	Both
LAEL147_000870300 isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007991	Both
LAEL147_000401300 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_005414 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007991	Both
LAEL147_000348700 alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007991	Both
LAEL147_000551200 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007991	Both
LAEL147_000322800 ⚠ aspartyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_003107 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003867 ↔ TCSYLVIO_007991	Both
LAEL147_000485900 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007991 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007991	Both
LAEL147_000554100 ⚠ co-chaperone GrpE, putative	—	OG6 TCSYLVIO_003139 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_003139 ↔ TCSYLVIO_007991	Both
LAEL147_000351600 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_007603 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_007603 ↔ TCSYLVIO_007991	Both
LAEL147_000664000 Gar1/Naf1 RNA binding region containing prote	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007991	Both
LAEL147_000148100 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007991	Both
LAEL147_000045300 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007991	Both
LAEL147_000283400 ⚠ ABC transport system ATP-binding protein, put	—	OG6 TCSYLVIO_006012 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007991	Both
LAEL147_000677000 hypothetical protein, conserved	—	OG6 TCSYLVIO_004910 ↔ TCSYLVIO_007991 OG7 TCSYLVIO_004910 ↔ TCSYLVIO_007991	Both
LAEL147_000553700 ⚠ nuclear movement protein, putative	—	OG7 TCSYLVIO_007991 ↔ TCSYLVIO_010327	OG7
LAEL147_000254200 ⚠ NOL1/NOP2/sun family, putative	—	OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007991	OG7
LAEL147_000269100 ⚠ Multisite-specific tRNA:(cytosine-C(5))-methy	—	OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007991	OG7
LAEL147_000522500 ⚠ heat shock protein 90, putative	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_007991	OG7
LAEL147_000668200 ⚠ heat shock protein 83-17	—	OG7 TCSYLVIO_005578 ↔ TCSYLVIO_007991	OG7
LAEL147_000812300 ⚠ dihydrouridine synthase domain protein-like p	—	OG7 TCSYLVIO_007991 ↔ TCSYLVIO_009102	OG7
LAEL147_000354300 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_007991 ↔ TCSYLVIO_010724	OG7
LAEL147_000606500 ⚠ dihydrouridine synthase (Dus), putative	—	OG7 TCSYLVIO_007991 ↔ TCSYLVIO_009102	OG7
LAEL147_000554200 ⚠ heat shock protein grpe	—	OG7 TCSYLVIO_003139 ↔ TCSYLVIO_007991	OG7
LAEL147_000387500 ⚠ translation initiation factor IF-2, putative	—	OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007991	OG7
LAEL147_000312000 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_006877 ↔ TCSYLVIO_007991	OG7
LAEL147_000311900 ⚠ hypothetical protein, conserved	—	OG7 TCSYLVIO_006877 ↔ TCSYLVIO_007991	OG7
LAEL147_000780700 ⚠ pentatricopeptide repeat domain containing pr	—	OG7 TCSYLVIO_000834 ↔ TCSYLVIO_007991	OG7

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