LAMA_000369400

ADP-ribosylation factor family/Ras of Complex, Roc, domain of DAPkinase/Ras family, putative
Leishmania amazonensis MHOM/BR/71973/M2269 OG6: OG6_105709 OG7: OG7_0000131 88 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 88 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LAMA_000702600
WD domain, G-beta repeat, putative
— OG6
LAMA_000324400 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG6
LAMA_000077700 ⚠
XRN 5'-3' exonuclease N-terminus/Xrn1 helical
— OG6
LAMA_000045900
Alcohol dehydrogenase GroES-like domain/Zinc-
— OG6
LAMA_000418500
Glutamine amidotransferase class-I/Peptidase
— OG6
LAMA_000254900
hypothetical protein, conserved
— OG6
LAMA_000342500 ⚠
Protein of unknown function (DUF2009), putati
— OG6
LAMA_000273900
GHMP kinases N terminal domain/Mevalonate 5-d
— OG6
LAMA_000222100
YjeF-related protein N-terminus/Carbohydrate
— OG6
LAMA_000019200
NPL4 family, putative
— OG6
LAMA_000247200
Amidohydrolase family, putative
— OG6
LAMA_000678800
hypothetical protein, conserved
— OG6
LAMA_000498600
hypothetical protein, conserved
— OG6
LAMA_000808200 ⚠
Protein of unknown function (DUF2009), putati
— OG6
LAMA_000491700
TAP42-like family, putative
— OG6
LAMA_000159700
Isocitrate/isopropylmalate dehydrogenase, put
— OG6
LAMA_000120600
U-box domain containing protein, putative
— OG6
LAMA_000633000
Biotin/lipoate A/B protein ligase family, put
— OG6
LAMA_000314900
eIF-6 family, putative
— OG6
LAMA_000535800
UBA/TS-N domain containing protein, putative
— OG6
LAMA_000655000
Myristoyl-CoA:protein N-myristoyltransferase,
— OG6
LAMA_000311700
Elongation factor Tu GTP binding domain/Elong
— OG6
LAMA_000675300 ⚠
Cytidylyltransferase-like, putative
— OG6
LAMA_000049500 ⚠
Inorganic pyrophosphatase, putative
— OG6
LAMA_000172400 ⚠
Inorganic pyrophosphatase, putative
— OG6
LAMA_000724400
Transcription factor S-II (TFIIS), putative
— OG6
LAMA_000624300
Ubiquitin family/Ubiquitin carboxyl-terminal
— OG6
LAMA_000005900
Cyclophilin type peptidyl-prolyl cis-trans is
— OG6
LAMA_000575600
Telomere recombination/Putative GTP-binding c
— OG6
LAMA_000420700
SEP domain containing protein, putative
— OG6
LAMA_000566500
Electron transfer flavoprotein domain/Electro
— OG6
LAMA_000453000
Alanine racemase, N-terminal domain containin
— OG6
LAMA_000275700 ⚠
Dephospho-CoA kinase, putative
— OG6
LAMA_000768100
Pyruvate kinase, barrel domain/Pyruvate kinas
— OG6
LAMA_000566200
WD domain, G-beta repeat, putative
— OG6
LAMA_000761200
Phosphoglucomutase/phosphomannomutase, alpha/
— OG6
LAMA_000663300
Alpha/beta hydrolase family/Serine aminopepti
— OG6
LAMA_000114700
Choline/Carnitine o-acyltransferase, putative
— OG6
LAMA_000775400 ⚠
Aminotransferase class I and II, putative
— OG6
LAMA_000457300 ⚠
Aminotransferase class I and II, putative
— OG6
LAMA_000611100
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG6
LAMA_000566800
haloacid dehalogenase-like hydrolase/Sucrose-
— OG6
LAMA_000249200
Transaldolase/Fructose-6-phosphate aldolase,
— OG6
LAMA_000374200
Metalloenzyme superfamily/BPG-independent PGA
— OG6
LAMA_000460000
Microtubule binding/Kinesin motor domain cont
— OG6
LAMA_000525000
Zn-finger in Ran binding protein and others/S
— OG6
LAMA_000352300
Protein of unknown function (DUF2870), putati
— OG6
LAMA_000383900
hypothetical protein, conserved
— OG6
LAMA_000311100 ⚠
Protein phosphatase 2C, putative
— OG6
LAMA_000552400 ⚠
Protein phosphatase 2C, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.