TcCLB.504215.10

hypothetical protein, conserved
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_152675 OG7: OG7_0000556 69 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 69 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509669.90
XPC-binding domain/UBA/TS-N domain containing
— OG6
TcCLB.510999.30
hypothetical protein, conserved
— OG6
TcCLB.511731.10
UV excision repair RAD23-like protein, putati
— OG6
TcCLB.506945.80
DNA ligase I, putative
— OG6
TcCLB.507993.260
hypothetical protein, conserved
— OG6
TcCLB.509801.10
hypothetical protein, conserved
— OG6
TcCLB.509965.350
ubiquitin-protein ligase, putative
— OG6
TcCLB.510101.250
hypothetical protein, conserved
— OG6
TcCLB.506733.80
hypothetical protein, conserved
— OG6
TcCLB.399033.19 ⚠
kinetoplast polyadenylation/uridylation facto
— OG6
TcCLB.503579.60
hypothetical protein
— OG6
TcCLB.509011.40
calreticulin, putative
— OG6
TcCLB.506773.80
hypothetical protein, conserved
— OG6
TcCLB.508215.9
protein kinase C substrate protein, heavy cha
— OG6
TcCLB.506405.40
hypothetical protein, conserved
— OG6
TcCLB.510997.30
hypothetical protein, conserved
— OG6
TcCLB.508465.110
acyl-CoA dehydrogenase, putative
— OG6
TcCLB.506363.130
tRNA (Uracil-5-)-methyltransferase, putative
— OG6
TcCLB.506699.3 ⚠
NOL1/NOP2/sun family, putative
— OG6
TcCLB.503613.60 ⚠
acidocalcisomal pyrophosphatase, putative
— OG6
TcCLB.508181.140 ⚠
inorganic pyrophosphatase, putative
— OG6
TcCLB.429257.10
Gar1/Naf1 RNA binding region, putative
— OG6
TcCLB.509595.50
DIS3-like exonuclease, putative
— OG6
TcCLB.506863.10
alanyl-tRNA synthetase, putative
— OG6
TcCLB.511627.100 ⚠
TPR-repeat protein, putative
— OG6
TcCLB.509757.30 ⚠
stress-inducible protein STI1-like, putative
— OG6
TcCLB.504125.60
Kinesin-13 3, putative
— OG6
TcCLB.509247.50
methionyl-tRNA synthetase, putative
— OG6
TcCLB.510321.20 ⚠
NOL1/NOP2/sun family, putative
— OG6
TcCLB.506289.60
Cupin-like domain containing protein, putativ
— OG6
TcCLB.504137.10
isoleucyl-tRNA synthetase, putative
— OG6
TcCLB.508387.10 ⚠
hypothetical protein, conserved
— OG6
TcCLB.510617.19 ⚠
hypothetical protein, conserved
— OG6
TcCLB.510533.120
translation initiation factor IF-2, putative
— OG6
TcCLB.509123.30 ⚠
kinetoplast polyadenylation/uridylation facto
— OG6
TcCLB.506743.80 ⚠
SMP-30/Gluconolaconase/LRE-like region, putat
— OG6
TcCLB.511049.40
leucyl-tRNA synthetase, putative
— OG6
TcCLB.509965.110
importin alpha, putative
— OG6
TcCLB.511421.60 ⚠
deoxyhypusine synthase, putative
— OG6
TcCLB.504119.29 ⚠
deoxyhypusine synthase, putative
— OG6
TcCLB.510599.30
Component of IIS longevity pathway SMK-1, put
— OG6
TcCLB.508207.240 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG6
TcCLB.511741.50 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— OG6
TcCLB.508723.80
disgorgin, putative
— OG6
TcCLB.503637.30
serine peptidase, Clan SC, Family S9B
— OG6
TcCLB.510603.110 ⚠
hypothetical protein, conserved
— OG6
TcCLB.503599.10
calcium/calmodulin-dependent protein kinase,
— OG6
TcCLB.506941.130
SET domain containing protein, putative
— OG6
TcCLB.509167.100
valyl-tRNA synthetase, putative
— OG6
TcCLB.509153.120
acyl-CoA dehydrogenase, putative
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.