TcYC6_0000440

Ankyrin repeats (3 copies)/Zinc finger, C3HC4 type (RING finger), putative
Trypanosoma cruzi Y C6 OG6: OG6_144850 OG7: OG7_0001851 49 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 49 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcYC6_0069310
hypothetical protein, conserved
— OG6
TcYC6_0040110 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0016320
ARM-like helical domain-containing protein
— OG6
TcYC6_0048370 ⚠
GMP reductase
— OG6
TcYC6_0111640
putative ATP-dependent DEAD/H RNA helicase
— OG6
TcYC6_0077260
translation initiation factor IF-2, putative
— OG6
TcYC6_0053230
HECT-domain (ubiquitin-transferase), putative
— OG6
TcYC6_0125510
hypothetical protein, conserved
— OG6
TcYC6_0031370
5'-AMP-activated protein kinase subunit beta,
— OG6
TcYC6_0110770
aspartyl aminopeptidase, putative
— OG6
TcYC6_0116560
prolyl-tRNA synthetase, putative
— OG6
TcYC6_0072130
hypothetical protein
— OG6
TcYC6_0095370
hypothetical protein, conserved
— OG6
TcYC6_0109960
hypothetical protein, conserved
— OG6
TcYC6_0115770
Zn-finger in Ran binding protein and others/F
— OG6
TcYC6_0043390
hypothetical protein, conserved
— OG6
TcYC6_0043810
metallo-peptidase, Clan MF, Family M17
— OG6
TcYC6_0089430
asparaginyl-tRNA synthetase, putative
— OG6
TcYC6_0071320
hypothetical protein, conserved
— OG6
TcYC6_0053280
hypothetical protein, conserved
— OG6
TcYC6_0112960 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— OG6
TcYC6_0116260
putative 5-oxoprolinase
— OG6
TcYC6_0067770
Casein kinase II
— OG6
TcYC6_0110900
protein kinase, putative
— OG6
TcYC6_0043360
PUB domain containing protein, putative
— OG6
TcYC6_0081900
putative replication factor C, subunit 1
— OG6
TcYC6_0093170
guide RNA associated protein, GAP2, putative
— OG6
TcYC6_0096730
microtubule associated protein xmap215
— OG6
TcYC6_0092200
R3H domain containing protein, putative
— OG6
TcYC6_0001300 ⚠
hypothetical protein
— OG6
TcYC6_0000160
Nop14-like family, putative
— OG6
TcYC6_0023240
Domain of unknown function (DUF4042), putativ
— OG6
TcYC6_0095890
ubiquitin-protein ligase
— OG6
TcYC6_0025640 ⚠
inosine-5'-monophosphate dehydrogenase, putat
— OG6
TcYC6_0040710 ⚠
hypothetical protein, conserved
— OG6
TcYC6_0066100
ubiquitin-activating enzyme
— OG6
TcYC6_0056290
protein farnesyltransferase, putative
— OG6
TcYC6_0107530
ATP-dependent RNA helicase, putative
— OG6
TcYC6_0031580
hypothetical protein, conserved
— OG6
TcYC6_0057350
hypothetical protein, conserved
— OG6
TcYC6_0084700
endo-beta-N-acetylglucosaminidase, putative
— OG6
TcYC6_0012520
p21-C-terminal region-binding protein, putati
— OG6
TcYC6_0089910
hypothetical protein, conserved
— OG6
TcYC6_0151390 ⚠
mucin TcMUCII, putative
— OG6
TcYC6_0107490
hypothetical protein, conserved
— OG6
TcYC6_0021560
U6 snRNA-associated Sm-like protein LSm7p
— OG6
TcYC6_0065870
hypothetical protein, conserved
— OG6
TcYC6_0116640
hypothetical protein, conserved
— OG6
TcYC6_0115710
hypothetical protein, conserved
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.