C4B63_44g238

ATP-dependent RNA helicase
Trypanosoma cruzi Dm28c 2018 OG6: OG6_146508 OG7: OG7_0000698 31 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 31 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_8g54
conserved hypothetical protein
— OG6
C4B63_12g208
leucine-rich repeat protein (LRRP)
— OG6
C4B63_31g99
WD repeat-containing protein 17
— OG6
C4B63_12g212 ⚠
conserved hypothetical protein
— OG6
C4B63_12g211 ⚠
conserved hypothetical protein
— OG6
C4B63_4g258
prolyl-tRNA synthetase
— OG6
C4B63_300g17 ⚠
E3 ubiquitin-protein ligase MGRN1
— OG6
C4B63_34g319 ⚠
E3 ubiquitin-protein ligase MGRN1
— OG6
C4B63_82g92 ⚠
conserved hypothetical protein
— OG6
C4B63_77g26 ⚠
conserved hypothetical protein
— OG6
C4B63_43g1065c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG6
C4B63_271g80c ⚠
U6 snRNA-associated Sm-like protein LSm7p
— OG6
C4B63_23g201
protein kinase
— OG6
C4B63_1g73 ⚠
conserved hypothetical protein
— OG6
C4B63_5g416 ⚠
conserved hypothetical protein
— OG6
C4B63_28g129
replication factor C, subunit 1
— OG6
C4B63_4g320
conserved hypothetical protein
— OG6
C4B63_42g65
ubiquitin-protein ligase
— OG6
C4B63_4g269
conserved hypothetical protein
— OG6
C4B63_42g187
conserved hypothetical protein
— OG6
C4B63_8g219 ⚠
protein farnesyltransferase
— OG6
C4B63_50g5 ⚠
protein farnesyltransferase
— OG6
C4B63_2g768
RNA-binding protein
— OG6
C4B63_84g82
DNA mismatch repair protein MSH2
— OG6
C4B63_2g376
ribosome assembly protein RRB1
— OG6
C4B63_69g26
endo-beta-N-acetylglucosaminidase
— OG6
C4B63_2g297
conserved hypothetical protein
— OG6
C4B63_17g98
E3 ubiquitin-protein ligase UPL3
— OG6
C4B63_102g53
conserved hypothetical protein
— OG6
C4B63_76g32
guide RNA associated protein, GAP2
— OG6
C4B63_31g76
ubiquitin-activating enzyme
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.