TcCLB.508995.10

STE group serine/threonine-protein kinase, putative
Trypanosoma cruzi CL Brener Esmeraldo-like OG6: OG6_147529 OG7: OG7_0000432 46 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:
Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 46 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
TcCLB.509625.10 ⚠
ATP-dependent RNA helicase, putative (fragmen
— OG6
TcCLB.506251.50
Cell division control protein 48, putative
— OG6
TcCLB.511545.100
RNA methyltransferase, putative
— OG6
TcCLB.510773.9 ⚠
Thioredoxin-like/Protein of unknown function
— OG6
TcCLB.504643.49
hypothetical protein, conserved (fragment)
— OG6
TcCLB.506625.200
exosome complex exonuclease, putative, riboso
— OG6
TcCLB.510311.50
hypothetical protein, conserved
— OG6
TcCLB.508387.70
Mono-functional DNA-alkylating methyl methane
— OG6
TcCLB.506357.140
Periodic tryptophan protein 2 homolog, putati
— OG6
TcCLB.511313.40 ⚠
ATP-dependent RNA helicase, putative
— OG6
TcCLB.506179.59 ⚠
ATP-dependent RNA helicase, putative (fragmen
— OG6
TcCLB.511315.9 ⚠
ATP-dependent RNA helicase, putative
— OG6
TcCLB.506673.60
Adaptor protein complex AP-3 subunit beta-3
— OG6
TcCLB.403789.9 ⚠
DNA-directed RNA polymerase I largest subunit
— OG6
TcCLB.443683.9 ⚠
DNA-directed rna polymerase I largest subunit
— OG6
TcCLB.506949.10 ⚠
DNA-directed rna polymerase I largest subunit
— OG6
TcCLB.401473.9 ⚠
DNA-directed RNA polymerase I largest subunit
— OG6
TcCLB.508839.89 ⚠
DNA-directed rna polymerase I largest subunit
— OG6
TcCLB.506661.110
WD domain, G-beta repeat/Dip2/Utp12 Family, p
— OG6
TcCLB.507809.30
ribose-phosphate pyrophosphokinase, putative
— OG6
TcCLB.507813.10 ⚠
structural maintenance of chromosome 3 protei
— OG6
TcCLB.503531.49 ⚠
structural maintenance of chromosome 3, putat
— OG6
TcCLB.506357.130
hypothetical protein, conserved
— OG6
TcCLB.506947.90 ⚠
adenylate kinase, putative
— OG6
TcCLB.506941.260
hypothetical protein, conserved
— OG6
TcCLB.510879.30
hypothetical protein, conserved
— OG6
TcCLB.510557.50 ⚠
mucin TcMUCII, putative
— OG6
TcCLB.508921.20 ⚠
hypothetical protein, conserved
— OG6
TcCLB.506945.359 ⚠
damage-specific DNA binding protein, putative
— OG6
TcCLB.508369.50 ⚠
acetyl-CoA carboxylase (fragment)
— OG6
TcCLB.504427.140
hypothetical protein, conserved
— OG6
TcCLB.506287.80
FYVE zinc finger, putative
— OG6
TcCLB.506925.40
RNA polymerase I second largest subunit, puta
— OG6
TcCLB.510771.9 ⚠
Thioredoxin-like/Protein of unknown function
— OG6
TcCLB.507093.63
RNA-binding protein, putative
— OG6
TcCLB.510747.130
hypothetical protein, conserved
— OG6
TcCLB.505807.270
ubiquitin hydrolase, putative, cysteine pepti
— OG6
TcCLB.510599.14 ⚠
acetyl-CoA carboxylase (fragment)
— OG6
TcCLB.509007.70
protein phosphatase 2C, putative
— OG6
TcCLB.510841.20 ⚠
hypothetical protein, conserved
— OG6
TcCLB.508131.19
Glycosyl hydrolase family 65 central catalyti
— OG6
TcCLB.509165.49 ⚠
damage-specific DNA binding protein, putative
— OG6
TcCLB.503479.30 ⚠
adenylate kinase 1
— OG6
TcCLB.503893.150
Right handed beta helix region/Periplasmic co
— OG6
TcCLB.503813.20
hypothetical protein, conserved
— OG6
TcCLB.505123.20 ⚠
hypothetical protein, conserved
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.