C4B63_55g91

NEDD4-like E3 ubiquitin-protein ligase WWP2
Trypanosoma cruzi Dm28c 2018 OG6: OG6_156487 OG7: OG7_0000785 61 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 61 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
C4B63_82g92 ⚠
conserved hypothetical protein
— OG6
C4B63_77g26 ⚠
conserved hypothetical protein
— OG6
C4B63_6g400 ⚠
conserved hypothetical protein
— OG6
C4B63_2g435
Flagellum attachment zone protein 12
— OG6
C4B63_235g21 ⚠
DeSI-like protein At4g17486
— OG6
C4B63_10g293
Phosphatidylinositol 4-phosphate 5-kinase 6
— OG6
C4B63_2g368
conserved hypothetical protein
— OG6
C4B63_58g130
vacuolar protein sorting-associated protein 3
— OG6
C4B63_23g186
aspartyl aminopeptidase
— OG6
C4B63_16g30 ⚠
poly(A)-specific ribonuclease PARN
— OG6
C4B63_7g79
aspartyl-tRNA synthetase
— OG6
C4B63_43g141
conserved hypothetical protein
— OG6
C4B63_1g43 ⚠
DeSI-like protein At4g17486
— OG6
C4B63_63g95 ⚠
poly(A)-specific ribonuclease PARN
— OG6
C4B63_282g21 ⚠
conserved hypothetical protein
— OG6
C4B63_101g26
conserved hypothetical protein
— OG6
C4B63_4g235 ⚠
5-oxoprolinase
— OG6
C4B63_32g238 ⚠
tubulin folding cofactor D
— OG6
C4B63_8g58
Dynein assembly factor 1, axonemal homolog
— OG6
C4B63_21g96
conserved hypothetical protein
— OG6
C4B63_5g416 ⚠
conserved hypothetical protein
— OG6
C4B63_1g73 ⚠
conserved hypothetical protein
— OG6
C4B63_23g275
ATP-dependent DEAD/H RNA helicase
— OG6
C4B63_2g765
cystathione gamma lyase
— OG6
C4B63_12g214 ⚠
zinc-finger ccch and cchc domain-containing p
— OG6
C4B63_12g213 ⚠
zinc-finger ccch and cchc domain-containing p
— OG6
C4B63_12g211 ⚠
conserved hypothetical protein
— OG6
C4B63_12g212 ⚠
conserved hypothetical protein
— OG6
C4B63_41g73 ⚠
Centrosomal protein of 164 kDa
— OG6
C4B63_31g99
WD repeat-containing protein 17
— OG6
C4B63_248g25 ⚠
Centrosomal protein of 164 kDa
— OG6
C4B63_28g76
Leucine-rich repeat-containing protein 9
— OG6
C4B63_21g264
protein transport protein SEC23
— OG6
C4B63_183g16 ⚠
conserved hypothetical protein
— OG6
C4B63_38g148 ⚠
DENN (AEX-3) domain containing protein
— OG6
C4B63_183g17 ⚠
conserved hypothetical protein
— OG6
C4B63_160g6 ⚠
poly(A)-specific ribonuclease PARN
— OG6
C4B63_42g187
conserved hypothetical protein
— OG6
C4B63_28g25
pyruvate dehydrogenase (lipoamide) kinase
— OG6
C4B63_24g197
nucleolar protein
— OG6
C4B63_4g258
prolyl-tRNA synthetase
— OG6
C4B63_2g297
conserved hypothetical protein
— OG6
C4B63_1g48 ⚠
Deubiquitinase DESI2
— OG6
C4B63_4g234 ⚠
5-oxoprolinase
— OG6
C4B63_42g205 ⚠
Eukaryotic translation initiation factor 4E-4
— OG6
C4B63_2g566
phenylalanyl-tRNA synthetase
— OG6
C4B63_51g105
conserved hypothetical protein
— OG6
C4B63_58g59 ⚠
conserved hypothetical protein
— OG6
C4B63_9g322
translation initiation factor IF-2
— OG6
C4B63_22g22 ⚠
ARM-like helical domain-containing protein
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.